Parkinson's Disease

被引：355

作者：

Reich, Stephen G. ^{[1
]}

Savitt, Joseph M. ^{[1
]}

机构：

[1] Univ Maryland, Dept Neurol, Sch Med, 110 South Paca St,3rd Floor, Baltimore, MD 21201 USA

来源：

MEDICAL CLINICS OF NORTH AMERICA | 2019年 / 103卷 / 02期

关键词：

Parkinsonism; Parkinson's disease; Tremor; Levodopa; Dyskinesias; REM sleep behavioral disorder; DEEP BRAIN-STIMULATION; PROGRESSIVE SUPRANUCLEAR PALSY; QUALITY-OF-LIFE; VASCULAR PARKINSONISM; CLINICAL-DIAGNOSIS; CARBIDOPA-LEVODOPA; NONMOTOR SYMPTOMS; DOUBLE-BLIND; THERAPY; AMANTADINE;

D O I：

10.1016/j.mcna.2018.10.014

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The diagnosis of Parkinson's disease (PD) is based on the presence of bradykinesia and either resting tremor or rigidity and there should be no features from the history or examination to suggest an alternative cause of parkinsonism. In addition to the motor manifestations of PD, there is a long list of nonmotor symptoms, several of which occur before motor signs and are considered "prodromal" PD. These are classified as neuropsychiatric, autonomic, sleep, and sensory. There are many medical options for the treatment of PD but levodopa remains the mainstay. Deep brain stimulation and other advanced therapies are also available.

引用

页码：337 / +

页数：16

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