Outcome Measures Used in Studies of Botulinum Toxin in Childhood Cerebral Palsy: A Systematic Review

被引:13
作者
Baird, Micah W. [1 ,2 ]
Vargus-Adams, Jilda [1 ,2 ,3 ]
机构
[1] Univ Cinncinati, Coll Med, Cincinnati Childrens Hosp, Med Ctr,Div Pediat Rehabil,Dept Pediat, Cincinnati, OH 45229 USA
[2] Univ Cinncinati, Coll Med, Cincinnati Childrens Hosp, Med Ctr,Dept Phys Med & Rehabil, Cincinnati, OH 45229 USA
[3] Univ Cinncinati, Coll Med, Cincinnati Childrens Hosp, Med Ctr,Ctr Epidemiol & Biostat, Cincinnati, OH 45229 USA
关键词
botulinum toxin; cerebral palsy; outcomes; International Classification of Functioning; Disability and Health; LOWER-LIMB SPASTICITY; GROSS MOTOR FUNCTION; A INJECTIONS; DOUBLE-BLIND; COMPREHENSIVE REHABILITATION; ADDUCTOR SPASTICITY; FUNCTIONAL OUTCOMES; RANDOMIZED-TRIAL; DYNAMIC EQUINUS; OPEN-LABEL;
D O I
10.1177/0883073809346846
中图分类号
R74 [神经病学与精神病学];
学科分类号
摘要
This literature review uses the International Classification of Functioning, Disability and Health to describe the quality and variety of the studies of botulinum toxin in children with cerebral palsy since 2001. Articles were identified via electronic query and then reviewed for strength of evidence and classification of outcome measures. The distribution of levels of evidence for the 63 articles was I (n = 8), II (n = 12), III (n =. 21), and IV (n = 22). One or more measurements were used in the International Classification of Functioning, Disability and Health domains of body structure and function (47 papers), activity (47 papers), participation (12 papers), and environmental/personal factors (10 papers). A total of 67% of all outcomes demonstrated a significant difference (I 49%, 1139%, III 74%, IV 88%). This review illustrates that few studies provide a high level of evidence and that outcomes focus on arenas such as spasticity or range of motion rather than activity or participation domains such as walking.
引用
收藏
页码:721 / 727
页数:7
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