Cervical transcutaneous vagal nerve stimulation (ctVNS) improves human cognitive performance under sleep deprivation stress

被引:38
|
作者
McIntire, Lindsey K. [1 ]
McKinley, R. Andy [2 ]
Goodyear, Chuck [1 ]
McIntire, John P. [3 ]
Brown, Rebecca D. [1 ]
机构
[1] Infoscitex Inc, Dayton, OH 45431 USA
[2] Air Force Res Lab, Appl Neurosci Branch, Wright Patterson AFB, OH USA
[3] Air Force Res Lab, Secur & Intelligence Branch, Wright Patterson AFB, OH USA
关键词
HUMAN-MACHINE INTERACTION; LOCUS-COERULEUS; MULTITASK PERFORMANCE; STRATEGY FUNCTION; CAFFEINE; VIGILANCE; FATIGUE; SYSTEM; MOOD;
D O I
10.1038/s42003-021-02145-7
中图分类号
Q [生物科学];
学科分类号
07 ; 0710 ; 09 ;
摘要
Fatigue is a pervasive public health and safety issue. Common fatigue countermeasures include caffeine or other chemical stimulants. These can be effective in limited circumstances but other non-pharmacological fatigue countermeasures such as non-invasive electrical neuromodulation have shown promise. It is reasonable to suspect that other types of non-invasive neuromodulation may be similarly effective or perhaps even superior. The objective of this research was to evaluate the efficacy of cervical transcutaneous vagal nerve stimulation (ctVNS) to mitigate the negative effects of fatigue on cognition and mood. Two groups (active or sham stimulation) of twenty participants in each group completed 34h of sustained wakefulness. The ctVNS group performed significantly better on arousal, multi-tasking, and reported significantly lower fatigue ratings compared to sham for the duration of the study. CtVNS could be a powerful fatigue countermeasure tool that is easy to administer, long-lasting, and has fewer side-effects compared to common pharmacological interventions. Lindsey McIntire et al. assess the impact of noninvasive cervical transcutaneous vagal nerve stimulation (ctVNS) on cognitive performance, mood, and attention in a cohort of sleep-deprived participants. Their results suggest that ctVNS can significantly improve arousal and multi-tasking, and may represent an alternative treatment for fatigue in humans.
引用
收藏
页数:9
相关论文
共 50 条
  • [31] A 2-WEEK COURSE OF TRANSCUTANEOUS VAGUS NERVE STIMULATION AND COGNITIVE PERFORMANCE
    Jandackova, Vera
    Vasendova, Veronika
    Jackowska, Marta
    Koenig, Julian
    PSYCHOSOMATIC MEDICINE, 2023, 85 (04): : A80 - A80
  • [32] Transcutaneous electrical nerve stimulation improves fatigue performance of the treated and contralateral knee extensors
    Behm, D. G.
    Colwell, E. M.
    Power, G. M. J.
    Ahmadi, H.
    Behm, A. S. M.
    Bishop, A.
    Murph, C.
    Pike, J.
    McAssey, B.
    Fraser, K.
    Kearley, S.
    Ryan, M.
    EUROPEAN JOURNAL OF APPLIED PHYSIOLOGY, 2019, 119 (11-12) : 2745 - 2755
  • [33] Transcutaneous electrical nerve stimulation improves fatigue performance of the treated and contralateral knee extensors
    D. G. Behm
    E. M. Colwell
    G. M. J. Power
    H. Ahmadi
    A. S. M. Behm
    A. Bishop
    C. Murph
    J. Pike
    B. McAssey
    K. Fraser
    S. Kearley
    M. Ryan
    European Journal of Applied Physiology, 2019, 119 : 2745 - 2755
  • [34] Transcutaneous vagal nerve stimulation protects against stress-induced intestinal barrier dysfunction in healthy adults
    Mogilevski, Tamara
    Rosella, Sam
    Aziz, Qasim
    Gibson, Peter R.
    NEUROGASTROENTEROLOGY AND MOTILITY, 2022, 34 (10):
  • [35] Cognitive performance after a 2-week course of transcutaneous vagus nerve stimulation
    Jandackova, V.
    Jackowska, M.
    Vasendova, V.
    Koenig, J.
    JOURNAL OF PSYCHOSOMATIC RESEARCH, 2023, 169 : 16 - 16
  • [36] Increasing off-time improves sleep-disordered breathing induced by vagal nerve stimulation
    Bhat, Sushanth
    Lysenko, Liudmila
    Neiman, Eli S.
    Rao, Gautami K.
    Chokroverty, Sudhansu
    EPILEPTIC DISORDERS, 2012, 14 (04) : 432 - 437
  • [37] Electric vagal nerve stimulation inhibits inflammation and improves early postoperation cognitive dysfunction in aged rats
    Jun Xiong
    Huijun Wang
    Yin Bao
    Yuliang Guo
    Yongxing Sun
    BMC Anesthesiology, 19
  • [38] Electric vagal nerve stimulation inhibits inflammation and improves early postoperation cognitive dysfunction in aged rats
    Xiong, Jun
    Wang, Huijun
    Bao, Yin
    Guo, Yuliang
    Sun, Yongxing
    BMC ANESTHESIOLOGY, 2019, 19 (01)
  • [39] Olfactory Epithelium Stimulation Using Rhythmic Nasal Air-Puffs Improves the Cognitive Performance of Individuals with Acute Sleep Deprivation
    Riazi, Hanieh
    Nazari, Milad
    Raoufy, Mohammad Reza
    Mirnajafi-Zadeh, Javad
    Shojaei, Amir
    BRAIN SCIENCES, 2024, 14 (04)
  • [40] Are there Sympathetic Nerve Fibers in Human Cervical and Thoracic Vagus Nerves?: Implications for Therapeutic Vagal Stimulation
    Seki, Atsuko
    Chen, Peng-Sheng
    Tan, Jian
    Fishbein, Michael C.
    CIRCULATION, 2013, 128 (22)