Behavioral Signatures of a Developing Neural Code

被引:13
作者
Avitan, Lilach [1 ,3 ]
Pujic, Zac [1 ]
Molter, Jan [1 ,2 ]
McCullough, Michael [1 ]
Zhu, Shuyu [1 ]
Sun, Biao [1 ]
Myhre, Ann-Elin [1 ]
Goodhill, Geoffrey J. [1 ,2 ]
机构
[1] Univ Queensland, Queensland Brain Inst, Brisbane, Qld 4072, Australia
[2] Univ Queensland, Sch Math & Phys, Brisbane, Qld 4072, Australia
[3] Hebrew Univ Jerusalem, Edmond & Lily Safra Ctr Brain Sci, IL-9190401 Jerusalem, Israel
基金
澳大利亚研究理事会;
关键词
LARVAL ZEBRAFISH; PREY CAPTURE; HUNTING BEHAVIOR; CIRCUITS; EMERGENCE; DYNAMICS; ONTOGENY; REVEALS; TECTUM;
D O I
10.1016/j.cub.2020.06.040
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
During early life, neural codes must develop to appropriately transform sensory inputs into behavioral outputs. Here, we demonstrate a link between the maturity of neural coding in the visual brain and developmental changes in visually guided behavior. In zebrafish larvae, we show that visually driven hunting behavior improves from 4 to 15 days post-fertilization, becoming faster and more accurate. During the same period, population activity in parts of the optic tectum refines, improving decoding and information transmission for particular spatial positions. Remarkably, individual differences in decoding can predict each fish's hunting success. Together, these results help reveal how the neural codes required for a natural behavior emerge during development.
引用
收藏
页码:3352 / +
页数:17
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