Analytical Investigation of a Split Double Gate Graded Channel Field Effect Transistor for Biosensing Applications

被引:2
作者
Singh, Khuraijam Nelson [1 ]
Dutta, Pranab Kishore [1 ]
机构
[1] NERIST, Dept ECE, Nirjuli 791109, Arunachal Prade, India
关键词
Analytical modeling; Biosensor; FET device; Label-free; Threshold voltage shift; Underlap; MOSFET; SENSITIVITY; PERFORMANCE;
D O I
10.1007/s12633-022-01774-9
中图分类号
O64 [物理化学(理论化学)、化学物理学];
学科分类号
070304 ; 081704 ;
摘要
A field-effect transistor (FET) based biosensor with nano-cavity on a single side has high sensing ability, improved binding probability, and better structural stability than a nanogap biosensor. However, the analyte size and the presence of nano-cavity result in high threshold voltage and lower driving capability. This paper presents a double gate graded channel FET with stacked dielectrics for label-free biosensing applications. Two symmetrical nano-cavities have been created in the gate oxides to bind the analytes. The primary analytes used in the analysis are DNA and avian influenza antibody (AI-ab). Suitable receptors for DNA and AI-ab have been used to enhance the device's selectivity. The analysis is done based on the surface potential and threshold voltage model. Additionally, variations in the electric field along the device channel have been modeled in order to gain a better understanding of the device's characteristics. In the study, the threshold voltage shift due to the analyte's binding is considered the sensing criterion. The results of the analysis have shown the superior sensing and driving capacity of the proposed device. The model results have been verified by using TCAD simulated data. Hence, the proposed device can be considered in the development of a portable, low cost FET device for biosensing applications with high sensing ability.
引用
收藏
页码:11303 / 11313
页数:11
相关论文
共 35 条
  • [1] Spindle cell lipoma masquerading as lipomatous pleomorphic adenoma: A diagnostic dilemma on fine needle aspiration cytology
    Agarwal, S.
    Nangia, A.
    Jyotsna, Lalita P.
    Pujani, M.
    [J]. JOURNAL OF CYTOLOGY, 2013, 30 (01) : 55 - 57
  • [2] Charge and dielectric effects of biomolecules on electrical characteristics of nanowire FET biosensors
    Ahn, Jae-Hyuk
    Choi, Sung-Jin
    Im, Maesoon
    Kim, Sungho
    Kim, Chang-Hoon
    Kim, Jee-Yeon
    Park, Tae Jung
    Lee, Sang Yup
    Choi, Yang-Kyu
    [J]. APPLIED PHYSICS LETTERS, 2017, 111 (11)
  • [3] Modeling of gate underlap junctionless double gate MOSFET as bio-sensor
    Ajay
    Narang, Rakhi
    Saxena, Manoj
    Gupta, Mridula
    [J]. MATERIALS SCIENCE IN SEMICONDUCTOR PROCESSING, 2017, 71 : 240 - 251
  • [4] Modeling and Simulation Investigation of Sensitivity of Symmetric Split Gate Junctionless FET for Biosensing Application
    Ajay
    Narang, Rakhi
    Saxena, Manoj
    Gupta, Mridula
    [J]. IEEE SENSORS JOURNAL, 2017, 17 (15) : 4853 - 4861
  • [6] One-step immunoassay without washing steps for influenza A virus detection using ISFET
    Bong, Ji-Hong
    Kim, Hong-Rae
    Yoo, Jae-Woo
    Kang, Min-Jung
    Shin, Myung-Geun
    Lee, Jung-Su
    Shim, Won-Bo
    Lee, Sang-Dae
    Pyun, Jae-Chul
    [J]. BIOSENSORS & BIOELECTRONICS, 2020, 165 (165)
  • [7] An Accurate Model for Threshold Voltage Analysis of Dual Material Double Gate Metal Oxide Semiconductor Field Effect Transistor
    Chakrabarti, Himeli
    Maity, Reshmi
    Baishya, S.
    Maity, N. P.
    [J]. SILICON, 2021, 13 (06) : 1851 - 1861
  • [8] Analytical modeling and sensitivity analysis of dielectric-modulated junctionless gate stack surrounding gate MOSFET (JLGSSRG) for application as biosensor
    Chakraborty, Avik
    Sarkar, Angsuman
    [J]. JOURNAL OF COMPUTATIONAL ELECTRONICS, 2017, 16 (03) : 556 - 567
  • [9] Simulation and Performance Analysis of Dielectric Modulated Dual Source Trench Gate TFET Biosensor
    Chong, Chen
    Liu, Hongxia
    Wang, Shulong
    Chen, Shupeng
    [J]. NANOSCALE RESEARCH LETTERS, 2021, 16 (01):
  • [10] Direct measurement of the dielectric polarization properties of DNA
    Cuervo, Ana
    Dans, Pablo D.
    Carrascosa, Jose L.
    Orozco, Modesto
    Gomila, Gabriel
    Fumagalli, Laura
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2014, 111 (35) : E3624 - E3630