Inappropriate low glycated hemoglobin and hemolysis

被引：8

作者：

Debard, A. ^{[1
]}

Charmion, S. ^{[1
]}

Ben Ameur, S. ^{[1
]}

Gaultier, J. -B. ^{[1
]}

Cathebras, P. ^{[1
]}

机构：

[1] Hop Nord St Etienne, Serv Med Interne, F-42055 St Etienne 2, France

来源：

REVUE DE MEDECINE INTERNE | 2009年 / 30卷 / 06期

关键词：

Glycosylated hemoglobin; Hemolysis; Evans syndrome; INDICATOR; VALUES;

D O I：

10.1016/j.revmed.2008.10.010

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hemoglobin A1c (HbA1c), measured regularly in the patients with diabetes, is the major form of stable glycated hemoglobin and has to be maintained below 6.5% to prevent or decrease the risk of chronic complications. HbA1c reflects mean blood glucose levels of the previous 3 months. We report the case of a particularly low HbA1c in a diabetic patient despite high plasma glucose levels, that was induced by auto-immune hemolysis related to an Evans syndrome. All hemolytic disorders can be responsible for falsely reassuring HbA1c values. Clinicians must be aware that hematologic status has to be considered for the correct interpretation of HbA1c results. (C) 2008 Elsevier Masson SAS. Tons droits reserves.

引用

页码：525 / 527

页数：3

共 10 条

[1]

Calisti Lorenza, 2005, Acta Biomed, V76 Suppl 3, P59

[2]

Daae LNW, 1999, CLIN CHEM, V45, P569

[3] Inappropriately low glycated hemoglobin values and hemolysis in HIV-infected patients [J].

Diop, Marie-Emilienne ;

Bastard, Jean-Philippe ;

Meunier, Natacha ;

Thevenet, Sandrine ;

Maachi, Mustapha ;

Capeau, Jacqueline ;

Pialoux, Gilles ;

Vigouroux, Corinne .

AIDS RESEARCH AND HUMAN RETROVIRUSES, 2006, 22 (12) :1242-1247

[4]

Gillery P, 2000, ANN BIOL CLIN-PARIS, V58, P425

[5] Glycated albumin is a better glycemic indicator than glycated hemoglobin values in hemodialysis patients with diabetes: Effect of anemia and erythropoietin injection [J].

Inaba, Masaaki ;

Okuno, Senji ;

Kumeda, Yasuro ;

Yamada, Shinsuke ;

Imanishi, Yasuo ;

Tabata, Tsutomu ;

Okamura, Mikio ;

Okada, Shigeki ;

Yamakawa, Tomoyuki ;

Ishimura, Eiji ;

Nishizawa, Yoshiki .

JOURNAL OF THE AMERICAN SOCIETY OF NEPHROLOGY, 2007, 18 (03) :896-903

[6]

Kutter D, 2006, CLIN LAB, V52, P477

[7] Warm autoimmune hemolytic anemias and Evans syndrome in adults [J].

Michel, M. .

REVUE DE MEDECINE INTERNE, 2008, 29 (02) :105-114

[8]

PANZER S, 1982, BLOOD, V59, P1348

[9]

Serratrice J, 2002, DIABETES METAB, V28, P508

[10] A falling HbA1c is not necessarily an indicator of improving diabetes control [J].

Wiener, K .

ANNALS OF CLINICAL BIOCHEMISTRY, 2001, 38 :406-407

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