Unusual Diffuse Ground-Glass Opacities in the Lungs on 18F-FDG PET/CT A Case of Melanoma With Pulmonary Metastasis

被引：0

作者：

Niu, Jinyun ^{[1
,2
]}

Quan, Zhiyong ^{[1
]}

Zhao, Xiaohu ^{[1
]}

Wang, Jing ^{[1
]}

Kang, Fei ^{[1
]}

机构：

[1] Fourth Mil Med Univ, Dept Nucl Med, Xijing Hosp, 15 Changle Xi Lu, Xian 710032, Shaanxi, Peoples R China

[2] Xian Cent Hosp, Dept Nucl Med, Xian, Peoples R China

来源：

CLINICAL NUCLEAR MEDICINE | 2022年 / 47卷 / 05期

关键词：

melanoma; pulmonary metastasis; F-18-FDG PET/CT; ground-glass opacities; MALIGNANT-MELANOMA;

D O I：

10.1097/RLU.0000000000004031

中图分类号：

R8 [特种医学]; R445 [影像诊断学];

学科分类号：

1002 ; 100207 ; 1009 ;

摘要：

A 61-year-old man was diagnosed with a malignant melanoma and underwent a resection; he presented with progressive dyspnea after treatment with interferon for 2 months. F-18-FDG PET/CT scan revealed diffuse ground-glass opacities (GGOs) in both lungs with mildly elevated F-18-FDG uptake, similar to that observed with interstitial inflammation. However, a lung biopsy confirmed that the diffuse GGOs were pulmonary metastases of melanoma and were positive for the BRAF mutation. The diffuse GGOs and the progressive dyspnea disappeared after BRAF-targeted therapy. This represents an unusual case of lung metastases from melanoma, mistakenly interpreted as lung inflammation induced by immunotherapy.

引用

页码：444 / 446

页数：3

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