The Effect of the Phospholipid Bilayer Environment on Cholesterol Crystal Polymorphism

被引:0
|
作者
Varsano, Neta
Beghi, Fabio
Dadosh, Tali
Elad, Nadav
Pereiro, Eva
Haran, Gilad
Leiserowitz, Leslie
Addadi, Lia
机构
[1] Department of Structural Biology, Weizmann Institute of Science, 234 Herzl Street, Rehovot
[2] Department of Chemistry, Università Degli Studi di Milano
[3] Department of Chemical Research Support, Weizmann Institute of Science
[4] MISTRAL Beamline-Experiments Division, ALBA Synchrotron Light Source Cerdanyola del Valles, Barcelona
[5] Department of Chemical & Biological Physics, Weizmann Institute of Science
[6] Department of Materials and Interfaces, Weizmann Institute of Science
来源
CHEMPLUSCHEM | 2019年 / 84卷 / 04期
关键词
atherosclerosis; cholesterol; crystal growth; pathological crystallization; polymorphism;
D O I
10.1002/cplu.201900121
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Invited for this month's cover are the group of Prof. Lia Addadi at the Weizmann Institute of Science, Israel and collaborators at the Universita Degli Studi di Milano, Italy, and the ALBA Synchrotron Light Source, Spain. The front cover shows how cholesterol crystals form in macrophage cells and in lipid bilayers of different compositions. Cholesterol monohydrate stable triclinic crystals form in vitro as rhomb-shaped plates, whereas the monoclinic crystals fold into tubular or helical shapes. Read the full text of the article at 10.1002/cplu.201800632.
引用
收藏
页码:317 / 317
页数:1
相关论文
共 50 条
  • [1] Effect of cholesterol on the structure of a phospholipid bilayer
    de Meyer, Frederick
    Smit, Berend
    PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 2009, 106 (10) : 3654 - 3658
  • [2] ASSEMBLY OF CHOLESTEROL IN PHOSPHOLIPID BILAYER
    HUANG, C
    BIOPHYSICAL JOURNAL, 1978, 21 (03) : A1 - A1
  • [3] Modulating membrane properties: The effect of trehalose and cholesterol on a phospholipid bilayer
    Doxastakis, M
    Sum, AK
    de Pablo, JJ
    JOURNAL OF PHYSICAL CHEMISTRY B, 2005, 109 (50): : 24173 - 24181
  • [4] Influence of Cholesterol on Phospholipid Bilayer Dynamics
    Boughter, Christopher T.
    Klauda, Jeffery B.
    BIOPHYSICAL JOURNAL, 2015, 108 (02) : 410A - 410A
  • [5] Cholesterol-like Condensing Effect of Perfluoroalkyl Substances on a Phospholipid Bilayer
    Shen, Zhiqiang
    Ge, Jeffrey
    Ye, Huilin
    Tang, Shan
    Li, Ying
    JOURNAL OF PHYSICAL CHEMISTRY B, 2020, 124 (26): : 5415 - 5425
  • [6] Cholesterol/phospholipid interactions in hybrid bilayer membranes
    Levy, Dustin
    Briggman, Kimberly A.
    LANGMUIR, 2007, 23 (13) : 7155 - 7161
  • [7] Cholesterol stabilizes hemifused phospholipid bilayer vesicles
    García, RA
    Pantazatos, SP
    Pantazatos, DP
    MacDonald, RC
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2001, 1511 (02): : 264 - 270
  • [8] Influence of Cholesterol on Phospholipid Bilayer Structure and Dynamics
    Boughter, Christopher T.
    Monje-Galvan, Viviana
    Im, Wonpil
    Klauda, Jeffery B.
    JOURNAL OF PHYSICAL CHEMISTRY B, 2016, 120 (45): : 11761 - 11772
  • [9] Bilayer undulation dynamics in unilamellar phospholipid vesicles: Effect of temperature, cholesterol and trehalose
    Bruning, Beate-Annette
    Prevost, Sylvain
    Stehle, Ralf
    Steitz, Roland
    Falus, Peter
    Farago, Bela
    Hellweg, Thomas
    BIOCHIMICA ET BIOPHYSICA ACTA-BIOMEMBRANES, 2014, 1838 (10): : 2412 - 2419
  • [10] INTERACTION OF AMPHOTERICIN-B AND NYSTATIN WITH PHOSPHOLIPID BILAYER MEMBRANES - EFFECT OF CHOLESTEROL
    SINGER, MA
    CANADIAN JOURNAL OF PHYSIOLOGY AND PHARMACOLOGY, 1975, 53 (06) : 1072 - 1079