Fertility Preservation in Childhood, Adolescent, and Young Adult Cancer 1 Fertility preservation for female patients with childhood , adolescent, and young adult cancer: recommendations from the PanCareLIFE Consortium and the International Late Effects of Childhood Cancer Guideline Harmonization Group

被引：0

作者：

Mulder, Renee L.

Font-Gonzalez, Anna ^{[1
]}

Hudson, Melissa M. ^{[4
,5
]}

van Santen, Hanneke M. ^{[6
]}

Loeffen, Erik A. H. ^{[8
]}

Burns, Karen C. ^{[9
,10
]}

Quinn, Gwendolyn P. ^{[11
,12
]}

van Dulmen-den Broeder, Eline ^{[2
]}

Byrne, Julianne ^{[13
]}

Haupt, Riccardo ^{[14
,15
]}

Wallace, W. Hamish ^{[17
]}

Heuvel-Eibrink, Marry M. van den ^{[18
]}

Anazodo, Antoinette ^{[20
,21
,22
]}

Anderson, Richard A. ^{[23
]}

Barnbrock, Anke ^{[24
]}

Beck, Joern D. ^{[25
,26
]}

Bos, Annelies M. E. ^{[7
]}

Demeestere, Isabelle ^{[27
]}

Denzer, Christian ^{[28
]}

Iorgi, Natascia Di ^{[16
]}

Hoefgen, Holly R. ^{[29
]}

Kebudi, Rejin ^{[30
,31
]}

Lambalk, Cornelis ^{[3
]}

Langer, Thorsten ^{[32
]}

Meacham, Lillian R. ^{[33
,34
,35
]}

Rodriguez-Wallberg, Kenny ^{[36
,37
]}

Stern, Catharyn ^{[38
,39
]}

Stutz-Grunder, Eveline ^{[40
]}

van Dorp, Wendy ^{[19
]}

Veening, Margreet ^{[2
]}

Veldkamp, Saskia ^{[1
]}

van der Meulen, Eline ^{[41
]}

Constine, Louis S. ^{[42
]}

Kenney, Lisa B. ^{[43
,44
]}

Wetering, Marianne D. van de

Kremer, Leontien C. M. ^{[1
]}

Levine, Jennifer ^{[45
]}

Tissing, Wim J. E. ^{[8
]}

机构：

[1] Univ Amsterdam, Emma Childrens Hosp, Pediat Oncol, Amsterdam UMC, Amsterdam, Netherlands

[2] Vrije Univ Amsterdam, Amsterdam UMC, Pediat Oncol, Emma Childrens Hosp, Amsterdam, Netherlands

[3] Vrije Univ Amsterdam, Dept Obstet & Gynecol, Amsterdam UMC, Amsterdam, Netherlands

[4] St Jude Childrens Res Hosp, Dept Epidemiol & Canc Control, 332 N Lauderdale St, Memphis, TN 38105 USA

[5] St Jude Childrens Res Hosp, Dept Oncol, 332 N Lauderdale St, Memphis, TN 38105 USA

[6] Wilhelmina Childrens Hosp, Dept Pediat Endocrinol, Utrecht, Netherlands

[7] UMC Utrecht, Dept Reprod Med & Gynaecol, Utrecht, Netherlands

[8] Univ Groningen, Beatrix Childrens Hosp, UMC Groningen, Dept Pediat Oncol Hematol, Groningen, Netherlands

[9] Cincinnati Childrens Hosp Med Ctr, Canc & Blood Dis Inst, Cincinnati, OH 45229 USA

[10] Univ Cincinnati, Coll Med, Dept Pediat, Cincinnati, OH USA

[11] NYU, Dept Obstet & Gynecol, Dept Populat Hlth, New York, NY 10003 USA

[12] NYU, Div Med Eth, New York, NY 10003 USA

[13] Boyne Res Inst, Drogheda, Ireland

[14] IRCCS Ist Giannina Gaslini, Epidemiol & Biostat Unit, Genoa, Italy

[15] IRCCS Ist Giannina Gaslini, DOPO Clinic, Genoa, Italy

[16] Univ Genova Genova, IRCCS Ist Giannina Gaslini, Dept Pediat, Genoa, Italy

[17] Royal Hosp Sick Children, Dept Paediat Haematol & Oncol, Edinburgh, Midlothian, Scotland

[18] Erasmus MC, Dept Pediat Hematol & Oncol, Div Reprod Med, Rotterdam, Netherlands

[19] Erasmus MC, Div Reprod Med, Dept Obstet & Gynaecol, Rotterdam, Netherlands

[20] Sydney Childrens Hosp, Kids Canc Ctr, Sydney, NSW, Australia

[21] Prince Wales Hosp, Nelune Comprehens Canc Ctr, Sydney, NSW, Australia

[22] Univ New S Wales, Sch Womens & Childrens Hlth, Sydney, NSW, Australia

[23] Univ Edinburgh, Med Res Council, Ctr Reprod Hlth, Edinburgh, Midlothian, Scotland

[24] Goethe Univ, Dept Children & Adolescents, Div Stem Cell Transplantat & Immunol, Univ Hosp, Frankfurt, Germany

[25] Univ Erlangen Nurnberg, Hosp Children & Adolescents, Erlangen, Germany

[26] Univ Lubeck, Hosp Children & Adolescents, LESS Grp, Lubeck, Germany

[27] Univ Libre Bruxelles, Res Lab Human Reprod & Fertil Clin, Dept Obstet & Gynecol, CU Hop Erasme, Brussels, Belgium

[28] Ulm Univ, Dept Pediat, Div Pediat Endocrinol & Diabet Adolescent Med, Med Ctr, Ulm, Germany

[29] Washington Univ, Sch Med, Div Pediat & Adolescent Gynecol, St Louis, MO USA

[30] Istanbul Univ Cerrahpasa, Cerrahpasa Med Fac, Div Pediat Hematol Oncol, Istanbul, Turkey

[31] Istanbul Univ, Oncol Inst, Istanbul, Turkey

[32] Univ Hosp Schleswig, Div Pediat Hematol & Oncol, Lubeck, Germany

[33] Childrens Healthcare Atlanta, Aflac Canc & Blood Disorders Ctr, Atlanta, GA USA

[34] Emory Univ, Div Hematol Oncol, Sch Med, Atlanta, GA 30322 USA

[35] Emory Univ, Div Endocrinol, Dept Pediat, Atlanta, GA 30322 USA

[36] Karolinska Univ Hosp, Dept Reprod Med, Div Gynecol & Reprod, Stockholm, Sweden

[37] Karolinska Inst, Dept Oncol Pathol, Stockholm, Sweden

[38] Melbourne IVF, East Melbourne, Vic, Australia

[39] Royal Womens Hosp, Reprod Serv, Melbourne, Vic, Australia

[40] Univ Zurich, Childrens Hosp Zurich, Dept Pediat Oncol, Zurich, Switzerland

[41] Dutch Childhood Canc Parent Org VOX, Nieuwegein, Netherlands

[42] Univ Rochester, Med Ctr, Dept Radiat Oncol, Dept Pediat, Rochester, NY USA

[43] Harvard Univ, Boston Childrens Hosp, Harvard Med Sch, Boston, MA 02115 USA

[44] Harvard Univ, Dana Farber Canc Inst, Harvard Med Sch, Boston, MA 02115 USA

[45] Cornell Univ, Div Pediat Hematol & Oncol, Weill Cornell Med, New York, NY USA

来源：

LANCET ONCOLOGY | 2021年 / 22卷 / 02期

关键词：

OVARIAN TISSUE CRYOPRESERVATION; CLINICAL-PRACTICE GUIDELINES; STEM-CELL TRANSPLANTATION; QUALITY-OF-LIFE; GONADAL-FUNCTION; SURVIVORS; PREGNANCY; CHILDREN; DISEASE; INSUFFICIENCY;

D O I：

暂无

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Female patients with childhood, adolescent, and young adult cancer are at increased risk for fertility impairment when treatment adversely affects the function of reproductive organs. Patients and their families desire biological children but substantial variations in clinical practice guidelines reduce consistent and timely implementation of effective interventions for fertility preservation across institutions. As part of the PanCareLIFE Consortium, and in collaboration with the International Late Effects of Childhood Cancer Guideline Harmonization Group, we reviewed the current literature and developed a clinical practice guideline for fertility preservation in female patients who were diagnosed with childhood, adolescent, and young adult cancer at age 25 years or younger, including guidance on risk assessment and available methods for fertility preservation. The Grading of Recommendations Assessment, Development and Evaluation methodology was used to grade the available evidence and to form the recommendations. This clinical practice guideline leverages existing evidence and international expertise to develop transparent recommendations that are easy to use to facilitate the care of female patients with childhood, adolescent, and young adult cancer who are at high risk for fertility impairment. A complete review of the existing evidence, including a quality assessment, transparent reporting of the guideline panel's decisions, and achievement of global interdisciplinary consensus, is an important result of this intensive collaboration.

引用

页码：E45 / E56

页数：12

共 84 条

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