[1] Bristol Heart Inst, Dept Cardiac Surg, Bristol, Avon, England
[2] Univ Bristol, Henry Welcome Labs Integrat Neurosci & Endocrinol, Bristol, Avon, England
[3] Bristol Royal Hosp Children, Dept Congenital Heart Surg, Bristol, Avon, England
[4] Univ Bristol, Clin Trial & Evaluat Unit, Bristol, Avon, England
[5] Univ Groningen, Dept Lab Med, Groningen, Netherlands
[6] Bristol Heart Inst, Dept Cardiac Anaesthesia, Bristol, Avon, England