Effects of CYP1A2*1C and CYP1A2*1F genotypes on the activity and inducibility of CYP1A2 determined by urinary caffeine metabolite ratio in Koreans

被引：0
作者：
Shin, Mi-Kyung [1 ]
Yi, Hyeon-Gyu [2 ]
Lee, Sung-Keun [1 ]
Park, Chang-Shin [1 ]
Kang, Ju-Hee [1 ]
机构：
[1] Inha Univ, Coll Med, Ctr Adv Med Educ, Inha Res Inst Med Sci Med Toxicol Res Dept Pharma, Inchon, South Korea
[2] Inha Univ Hosp, Dept Internal Med, Inchon, South Korea
来源：
MOLECULAR & CELLULAR TOXICOLOGY | 2007年 / 3卷 / 04期
关键词：
D O I：
暂无
中图分类号：
Q5 [生物化学]; Q7 [分子生物学];
学科分类号：
071010 ; 081704 ;
摘要：
引用
收藏
页码：62 / 62
页数：1
相关论文
共 14 条
  • [1] Effects of genetic polymorphisms of MDR1, FMO3 and CYP1A2 on susceptibility to colorectal cancer in Koreans
    Bae, Sun-Young
    Choi, Sun-Keun
    Kim, Kyung-Rae
    Park, Chang-Shin
    Lee, Sung-Keun
    Roh, Hyung-Keun
    Shin, Dong-Woon
    Pie, Jae-Eun
    Woo, Ze-Hong
    Kang, Ju-Hee
    [J]. CANCER SCIENCE, 2006, 97 (08) : 774 - 779
  • [2] HUMAN CYTOCHROME P-450PA (P-450IA2), THE PHENACETIN O-DEETHYLASE, IS PRIMARILY RESPONSIBLE FOR THE HEPATIC 3-DEMETHYLATION OF CAFFEINE AND N-OXIDATION OF CARCINOGENIC ARYLAMINES - (AROMATIC-AMINES HETEROCYCLIC AMINES CARCINOGEN METABOLISM)
    BUTLER, MA
    IWASAKI, M
    GUENGERICH, FP
    KADLUBAR, FF
    [J]. PROCEEDINGS OF THE NATIONAL ACADEMY OF SCIENCES OF THE UNITED STATES OF AMERICA, 1989, 86 (20) : 7696 - 7700
  • [3] Detection of three genetic polymorphisms in the 5′-flanking region and intron 1 of human CYP1A2 in the Japanese population
    Chida, M
    Yokoi, T
    Fukui, T
    Kinoshita, M
    Yokota, J
    Kamataki, T
    [J]. JAPANESE JOURNAL OF CANCER RESEARCH, 1999, 90 (09): : 899 - 902
  • [4] Effect of age and smoking on in vivo CYP1A2, flavin-containing monooxygenase, and xanthine oxidase activities in Koreans: Determination by caffeine metabolism
    Chung, WG
    Kang, JH
    Park, CS
    Cho, MH
    Cha, YN
    [J]. CLINICAL PHARMACOLOGY & THERAPEUTICS, 2000, 67 (03) : 258 - 266
  • [5] Comparisons of CYP1A2 genetic polymorphisms, enzyme activity and the genotype-phenotype relationship in Swedes and Koreans
    Ghotbi, Roza
    Christensen, Magnus
    Roh, Hyung-Keun
    Ingelman-Sundberg, Magnus
    Aklillu, Eleni
    Bertilsson, Leif
    [J]. EUROPEAN JOURNAL OF CLINICAL PHARMACOLOGY, 2007, 63 (06) : 537 - 546
  • [6] Inducibility of CYP1A2 by orneprazole in vivo related to the genetic polymorphism of CYP1A2
    Han, XM
    Ouyang, DS
    Chen, XP
    Shu, Y
    Jiang, CH
    Tan, ZR
    Zhou, HH
    [J]. BRITISH JOURNAL OF CLINICAL PHARMACOLOGY, 2002, 54 (05) : 540 - 543
  • [7] Plasma caffeine metabolite ratio (17X/137X) in vivo associated with G-2964A and C734A polymorphisms of human CYP1A2
    Han, XM
    Ou-Yang, DS
    Lu, PX
    Jiang, CH
    Shu, Y
    Chen, XP
    Tan, ZR
    Zhou, HH
    [J]. PHARMACOGENETICS, 2001, 11 (05): : 429 - 435
  • [8] Effects of genetic polymorphism of CYP1A2 inducibility on the steady-state plasma concentrations of trazodone and its active metabolite m-chlorophenylpiperazine in depressed Japanese patients
    Mihara, K
    Kondo, T
    Suzuki, A
    Yasui-Furukori, N
    Ono, S
    Otani, K
    Kaneko, S
    [J]. PHARMACOLOGY & TOXICOLOGY, 2001, 88 (05): : 267 - 270
  • [9] The CYP1A2-164A→C polymorphism (CYP1A2*1F) is associated with the risk for colorectal adenomas in humans
    Moonen, H
    Engels, L
    Kleinjans, J
    de Kok, T
    [J]. CANCER LETTERS, 2005, 229 (01) : 25 - 31
  • [10] NAKAJIMA M, 1994, CANCER EPIDEM BIOMAR, V3, P413
12