Introduction: Both migraine and mood disorders are prevalent disorders with many studies demonstrating that they are comorbid with each other with increased migraine-related disability in such patients. Aim: The aim of the study is to test the hypothesis that mood disorders are comorbid with migraine with increased disability and to identify any clinical features in migraineurs which may be associated with mood disorders. Materials and Methods: Patients presenting with complaints of headache to the Neurology Outpatient Department of a Tertiary CARE Hospital from August 01, 2016 to February 28, 2017, were subjected to International Classification of Headache Disorder 3 beta criteria to satisfy a diagnosis of migraine and were assessed in detail as to headache characteristics. Mood disorders were assessed by Hospital Anxiety and Depression Scale and migraine-related disability was assessed by Migraine Disability Assessment Questionnaire. Patients with serious medical complaints, known previous psychiatric disease, other types of headaches and recent prophylactic drug intake were carefully excluded. Results: A total of 133 patients were studied. The duration and frequency of migraine headaches were found to correlate with the presence of mood disorders and the migraine-related disability in patients with comorbid mood disorders was significantly higher. Factors such as total duration of migraine, aura, vomiting, phono, and photophobia were not found to be statistically correlated with mood disorders. Conclusions: Rates of depression and anxiety in migraine vary widely in various studies due to variations in study criteria, population characteristics and various scales used. We found a prevalence of 16.54% of anxiety and 9.02% of depression in migraineurs, a rate comparable to or less than many studies in international literature and a significantly increased disability in individuals with comorbid mood disorders and migraine. Routinely including questionnaires such as HAD in screening patients with migraine to rule out comorbid mood disorders may be warranted. Because we have carefully excluded all other primary (especially tension and medication overuse headaches) and secondary headaches and selected prophylactic drug naive patients, we contend that this study provides a clear clinical profile of migraineurs with mood disorders.
机构:
Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USA
Beth Israel Deaconess Med Ctr, Albert Einstein Coll Med, Dept Pain Med & Palliat Care, New York, NY 10003 USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Ashina, Sait
Serrano, Daniel
论文数: 0引用数: 0
h-index: 0
机构:
Vedanta Res, Chapel Hill, NC USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Serrano, Daniel
Lipton, Richard B.
论文数: 0引用数: 0
h-index: 0
机构:
Montefiore Headache Ctr, Bronx, NY 10461 USA
Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Lipton, Richard B.
Maizels, Morris
论文数: 0引用数: 0
h-index: 0
机构:
Blue Ridge Headache Ctr, Asheville, NC USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Maizels, Morris
Manack, Aubrey N.
论文数: 0引用数: 0
h-index: 0
机构:
Allergan Pharmaceut Inc, Irvine, CA USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Manack, Aubrey N.
Turkel, Catherine C.
论文数: 0引用数: 0
h-index: 0
机构:
Allergan Pharmaceut Inc, Irvine, CA USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Turkel, Catherine C.
Reed, Michael L.
论文数: 0引用数: 0
h-index: 0
机构:
Vedanta Res, Chapel Hill, NC USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Reed, Michael L.
Buse, Dawn C.
论文数: 0引用数: 0
h-index: 0
机构:
Montefiore Headache Ctr, Bronx, NY 10461 USA
Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USAMontefiore Headache Ctr, Bronx, NY 10461 USA
机构:
Merck Res Labs, Global Ctr Sci Affairs, Whitehouse Stn, NJ 08889 USA
Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USAMerck Res Labs, Global Ctr Sci Affairs, Whitehouse Stn, NJ 08889 USA
Bigal, Marcelo E.
Lipton, Richard B.
论文数: 0引用数: 0
h-index: 0
机构:
Montefiore Headache Ctr, Bronx, NY USA
Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USAMerck Res Labs, Global Ctr Sci Affairs, Whitehouse Stn, NJ 08889 USA
机构:
Montefiore Headache Ctr, Bronx, NY 10461 USA
Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Buse, D. C.
Manack, A.
论文数: 0引用数: 0
h-index: 0
机构:
Allergan Pharmaceut Inc, Irvine, CA 92715 USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Manack, A.
Serrano, D.
论文数: 0引用数: 0
h-index: 0
机构:
Vedanta Res, Chapel Hill, NC USA
Univ N Carolina, LL Thurstone Psychometr Lab, Chapel Hill, NC USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Serrano, D.
Turkel, C.
论文数: 0引用数: 0
h-index: 0
机构:
Allergan Pharmaceut Inc, Irvine, CA 92715 USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Turkel, C.
Lipton, R. B.
论文数: 0引用数: 0
h-index: 0
机构:
Montefiore Headache Ctr, Bronx, NY 10461 USA
Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USAMontefiore Headache Ctr, Bronx, NY 10461 USA
机构:
Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USA
Beth Israel Deaconess Med Ctr, Albert Einstein Coll Med, Dept Pain Med & Palliat Care, New York, NY 10003 USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Ashina, Sait
Serrano, Daniel
论文数: 0引用数: 0
h-index: 0
机构:
Vedanta Res, Chapel Hill, NC USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Serrano, Daniel
Lipton, Richard B.
论文数: 0引用数: 0
h-index: 0
机构:
Montefiore Headache Ctr, Bronx, NY 10461 USA
Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Lipton, Richard B.
Maizels, Morris
论文数: 0引用数: 0
h-index: 0
机构:
Blue Ridge Headache Ctr, Asheville, NC USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Maizels, Morris
Manack, Aubrey N.
论文数: 0引用数: 0
h-index: 0
机构:
Allergan Pharmaceut Inc, Irvine, CA USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Manack, Aubrey N.
Turkel, Catherine C.
论文数: 0引用数: 0
h-index: 0
机构:
Allergan Pharmaceut Inc, Irvine, CA USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Turkel, Catherine C.
Reed, Michael L.
论文数: 0引用数: 0
h-index: 0
机构:
Vedanta Res, Chapel Hill, NC USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Reed, Michael L.
Buse, Dawn C.
论文数: 0引用数: 0
h-index: 0
机构:
Montefiore Headache Ctr, Bronx, NY 10461 USA
Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USAMontefiore Headache Ctr, Bronx, NY 10461 USA
机构:
Merck Res Labs, Global Ctr Sci Affairs, Whitehouse Stn, NJ 08889 USA
Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USAMerck Res Labs, Global Ctr Sci Affairs, Whitehouse Stn, NJ 08889 USA
Bigal, Marcelo E.
Lipton, Richard B.
论文数: 0引用数: 0
h-index: 0
机构:
Montefiore Headache Ctr, Bronx, NY USA
Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USAMerck Res Labs, Global Ctr Sci Affairs, Whitehouse Stn, NJ 08889 USA
机构:
Montefiore Headache Ctr, Bronx, NY 10461 USA
Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Buse, D. C.
Manack, A.
论文数: 0引用数: 0
h-index: 0
机构:
Allergan Pharmaceut Inc, Irvine, CA 92715 USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Manack, A.
Serrano, D.
论文数: 0引用数: 0
h-index: 0
机构:
Vedanta Res, Chapel Hill, NC USA
Univ N Carolina, LL Thurstone Psychometr Lab, Chapel Hill, NC USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Serrano, D.
Turkel, C.
论文数: 0引用数: 0
h-index: 0
机构:
Allergan Pharmaceut Inc, Irvine, CA 92715 USAMontefiore Headache Ctr, Bronx, NY 10461 USA
Turkel, C.
Lipton, R. B.
论文数: 0引用数: 0
h-index: 0
机构:
Montefiore Headache Ctr, Bronx, NY 10461 USA
Albert Einstein Coll Med, Dept Neurol, Bronx, NY 10467 USAMontefiore Headache Ctr, Bronx, NY 10461 USA