共 1 条
[1]
Takeuchi T, 2022, INFLAMM REGEN, V42, DOI 10.1186/s41232-022-00221-x
Cytokines and cytokine receptors as targets of immune-mediated inflammatory diseases-RA as a role model (vol 42, 35, 2022)
被引：2
作者：
Takeuchi, Tsutomu
[1
,2
]
机构：
[1] Saitama Med Univ, 38 Morohongo, Iruma, Saitama 3500495, Japan
[2] Keio Univ, Sch Med, Dept Internal Med, Div Rheumatol, 35 Shinanomachi,Shinjuku, Tokyo 1608582, Japan
关键词：
Biological agents;
Cytokine;
Cytokine receptor;
Immune-mediated inflammatory diseases;
JAK inhibitors;
D O I：
10.1186/s41232-022-00250-6
中图分类号：
R392 [医学免疫学];
Q939.91 [免疫学];
学科分类号：
100102 ;
摘要：
Recent advances in our understanding in the immune-mediated inflammatory diseases (IMID) are explored and promoted by the targeted treatment. Among these targets, cytokines and cytokine receptors have become the good candidates for the drug development. In this review, the cytokine and cytokine receptors, which are approved in IMID, are overviewed, and modalities of the treatment, the role of cytokines and cytokine receptors in each disease, and the updated molecular information by modern technologies in rheumatoid arthritis as a role model are shown and discussed for the future perspectives. © 2022, The Author(s).
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