Solubility and thermodynamic properties of N-phenylanthranilic acid in Water plus Methanol/Ethanol/tert-butanol binary solvents from 283.15 K to 323.15 K

被引：5
作者：
Luo, Jiaqi [1 ]
Wang, Yingchen [1 ]
Shi, Chuncheng [2 ]
Zhang, Fan [3 ]
Yu, Qiushuo [1 ]
机构：
[1] Northwest Univ, Sch Chem Engn, Taibai North Rd 229, Xian 710069, Shaanxi, Peoples R China
[2] Xian Int Univ, Sch Med, Dept Pharm, Xian 710077, Shaanxi, Peoples R China
[3] Univ Sussex, Dept Engn & Design, Brighton BN1 9RH, E Sussex, England
来源：
JOURNAL OF CHEMICAL THERMODYNAMICS | 2022年 / 168卷
基金：
中国国家自然科学基金;
关键词：
N-phenylanthranilic acid; Solubility; Thermodynamic Properties; Binary solvent; ENTHALPY-ENTROPY COMPENSATION; CRYSTALLIZATION; COMPLEXES; MIXTURES; ETHANOL; DRUGS;
D O I：
10.1016/j.jct.2022.106748
中图分类号：
O414.1 [热力学];
学科分类号：
摘要：
The solubility of N-phenylanthranilic acid in water + tert-butanol/ethanol/methanol was determined by gravimetric method in the temperature range of (283.15 similar to 323.15) K at atmospheric pressure. Within this temperature range, the solubility increased with increase in the temperature. The descending order of the mole fraction solubility in binary solvents was as follow: water + tert-butanol > water + ethanol > water + methanol. The solubility was correlated by the Jouyban - Acree model. The van't Hoff equation was employed to analyze the thermodynamic properties of dissolution process including the Gibbs energy, enthalpy and entropy. The knowledge of solubility and thermodynamic properties is essential for design of the crystallization and purification of N-phenylanthranilic acid.
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页数：10
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