Imaging Characteristics of Coexisting Metastatic Papillary Thyroid Cancer and Prostate Cancer on 18F-Fluciclovine and 68Ga-PSMA-11 PET/CT

被引:3
作者
Lu, Yang [1 ]
机构
[1] Univ Texas MD Anderson Canc Ctr, Dept Nucl Med, Div Diagnost Imaging, 1400 Pressler St,Unit 1483, Houston, TX 77030 USA
关键词
Ga-68-PSMA-11; PET; F-18-fluciclovine PET; thyroid cancer; prostate cancer; metastasis; TRANSPORT; ACID; EXPRESSION;
D O I
10.1097/RLU.0000000000004156
中图分类号
R8 [特种医学]; R445 [影像诊断学];
学科分类号
1002 ; 100207 ; 1009 ;
摘要
A 76-year-old man with biopsy-proven metastatic papillary thyroid cancer in a mediastinal nodule status post total thyroidectomy is on surveillance. The patient also had prostate cancer and received prostatectomy and androgen deprivation treatment. An F-18-fluciclovine PET revealed avid lesions in the mediastinal nodule and a sclerotic focus at L5 with concurrent prostate-specific antigen level of 0.4 ng/mL. The L5 lesion was later biopsied and confirmed as metastasis from prostate cancer. A Ga-68-PSMA-11 PET 2 months later showed avid radiotracer uptake within L5 metastasis but not the mediastinal nodule. The patient received radiation therapy to the L5 lesion and responded well.
引用
收藏
页码:820 / 821
页数:2
相关论文
共 12 条
[1]   The Impact of Positron Emission Tomography with 18F-Fluciclovine on the Treatment of Biochemical Recurrence of Prostate Cancer: Results from the LOCATE Trial [J].
Andriole, Gerald L. ;
Kostakoglu, Lale ;
Chau, Albert ;
Duan, Fenghai ;
Mahmood, Umar ;
Mankoff, David A. ;
Schuster, David M. ;
Siegel, Barry A. ;
Adler, Lee P. ;
Belkoff, Laurence H. ;
Burzon, Daniel ;
Dato, Paul ;
Farwell, Michael ;
Fogelson, Stephen ;
Gardiner, Peter ;
Hanna, Lucy ;
Hoffman, John M. ;
Intenzo, Charles ;
Josephson, David ;
Kaminetsky, Jed ;
Kipper, Michael ;
Krynyckyi, Borys ;
Linder, Karen E. ;
Marques, Helga ;
Melnick, John ;
Miller, Matthew P. ;
Oh, William ;
Philips, Shaile ;
Rose, Judith ;
Savir-Baruch, Bital ;
Stevens, Daniel J. ;
Tewari, Ashutosh ;
Twardowski, Przemyslaw ;
Ward, Penelope ;
Wasserman, Martha ;
Weick, Sharon ;
Yu, Jian Q. .
JOURNAL OF UROLOGY, 2019, 201 (02) :322-330
[2]  
Chang SS, 1999, CANCER RES, V59, P3192
[3]  
ISRAELI RS, 1993, CANCER RES, V53, P227
[4]   Imaging Characteristics of Coexisting Primary Pulmonary Carcinoid Tumor and Multiple Myeloma on 18F-FDG and 68Ga-DOTATATE PET/CT [J].
Lu, Yang .
CLINICAL NUCLEAR MEDICINE, 2019, 44 (11) :914-915
[5]   Prostate-specific membrane antigen (PSMA) protein expression in normal and neoplastic tissues and its sensitivity and specificity in prostate adenocarcinoma: an immunohistochemical study using mutiple tumour tissue microarray technique [J].
Mhawech-Fauceglia, P. ;
Zhang, S. ;
Terracciano, L. ;
Sauter, G. ;
Chadhuri, A. ;
Herrmann, F. R. ;
Penetrante, R. .
HISTOPATHOLOGY, 2007, 50 (04) :472-483
[6]   Transport mechanisms of trans-1-amino-3-fluoro[1-14C] cyclobutanecarboxylic acid in prostate cancer cells [J].
Oka, Shuntaro ;
Okudaira, Hiroyuki ;
Yoshida, Yasunori ;
Schuster, David M. ;
Goodman, Mark M. ;
Shirakami, Yoshifumi .
NUCLEAR MEDICINE AND BIOLOGY, 2012, 39 (01) :109-119
[7]   Putative Transport Mechanism and Intracellular Fate of Trans-1-Amino-3-18F-Fluorocyclobutanecarboxylic Acid in Human Prostate Cancer [J].
Okudaira, Hiroyuki ;
Shikano, Naoto ;
Nishii, Ryuichi ;
Miyagi, Tohru ;
Yoshimoto, Mitsuyoshi ;
Kobayashi, Masato ;
Ohe, Kazuyo ;
Nakanishi, Takeo ;
Tamai, Ikumi ;
Namiki, Mikio ;
Kawai, Keiichi .
JOURNAL OF NUCLEAR MEDICINE, 2011, 52 (05) :822-829
[8]   Update on 18F-Fluciclovine PET for Prostate Cancer Imaging [J].
Parent, Ephraim E. ;
Schuster, David M. .
JOURNAL OF NUCLEAR MEDICINE, 2018, 59 (05) :733-739
[9]   ACR-ACNM Practice Parameter for the Performance of Fluorine-18 Fluciclovine-PET/CT for Recurrent Prostate Cancer [J].
Savir-Baruch, Bital ;
Banks, Kevin P. ;
McConathy, Jonathan E. ;
Molchanova-Cook, Olga P. ;
Parent, Ephraim E. ;
Takalkar, Amol ;
Tulchinsky, Mark ;
Yu, Jian Q. ;
Subramaniam, Rathan M. ;
Schuster, David M. .
CLINICAL NUCLEAR MEDICINE, 2018, 43 (12) :909-917
[10]   Prostate-specific membrane antigen in breast cancer: a comprehensive evaluation of expression and a case report of radionuclide therapy [J].
Tolkach, Yuri ;
Gevensleben, Heidrun ;
Bundschuh, Ralph ;
Koyun, Aydan ;
Huber, Daniela ;
Kehrer, Christina ;
Hecking, Thomas ;
Keyver-Paik, Mignon-Denise ;
Kaiser, Christina ;
Ahmadzadehfar, Hojjat ;
Essler, Markus ;
Kuhn, Walther ;
Kristiansen, Glen .
BREAST CANCER RESEARCH AND TREATMENT, 2018, 169 (03) :447-455