Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part II

被引:274
作者
Beckman, Joshua A. [1 ,2 ]
Paneni, Francesco [3 ,4 ]
Cosentino, Francesco [3 ,5 ]
Creager, Mark A. [1 ,2 ]
机构
[1] Brigham & Womens Hosp, Div Cardiovasc, Boston, MA 02115 USA
[2] Harvard Univ, Sch Med, Boston, MA 02115 USA
[3] Univ Zurich, Zurich, Switzerland
[4] IRCCS Neuromed, Pozzilli, Italy
[5] Univ Roma La Sapienza, Dept Clin & Mol Med, I-00185 Rome, Italy
关键词
Diabetes; Vascular disease; Medical therapy; ACUTE CORONARY SYNDROMES; PERIPHERAL-ARTERIAL-DISEASE; ACUTE MYOCARDIAL-INFARCTION; NUTRITION EXAMINATION SURVEY; CONVERTING-ENZYME-INHIBITOR; IMPAIRED GLUCOSE-TOLERANCE; LOWER-EXTREMITY AMPUTATION; TRANSIENT ISCHEMIC ATTACK; MRC/BHF HEART PROTECTION; SIROLIMUS-ELUTING STENTS;
D O I
10.1093/eurheartj/eht142
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
In part II of this review, we describe the epidemiology and clinical consequences of vascular disease in patients with diabetes, and discuss the efficacy of risk factor modification and antiplatelet treatment. Specifically, evidence-based cardiovascular therapies are discussed through novel clinical insights on management of hyperglycaemia, hypertension, dyslipidaemia as well as platelet dysfunction. Recent trends in the incidence and outcomes of vascular disease in diabetes suggest that timely and effective implementation of therapies is making a favourable impact.
引用
收藏
页码:2444 / U31
页数:13
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