ESC Council on hypertension position document on themanagement of hypertensive emergencies

被引：166

作者：

van den Born, Bert-Jan H. ^{[1
]}

Lip, Gregory Y. H. ^{[2
,3
]}

Brguljan-Hitij, Jana ^{[4
]}

Cremer, Antoine ^{[5
,6
]}

Segura, Julian ^{[7
]}

Morales, Enrique ^{[7
]}

Mahfoud, Felix ^{[8
]}

Amraoui, Fouad ^{[1
]}

Persu, Alexandre ^{[9
,10
]}

Kahan, Thomas ^{[11
]}

Rosei, Enrico Agabiti ^{[12
,13
]}

de Simone, Giovanni ^{[14
]}

Gosse, Philippe ^{[5
,6
]}

Williams, Bryan ^{[15
,16
]}

机构：

[1] Acad Med Ctr, Dept Internal Med, Div Vasc Med, Amsterdam, Netherlands

[2] Univ Birmingham, Inst Cardiovasc Sci, Birmingham, W Midlands, England

[3] Aalborg Univ, Fac Hlth, Dept Clin Med, Aalborg Thrombosis Res Unit, Aalborg, Denmark

[4] Dr Peter Drzaj Hosp, Univ Med Ctr Ljubljana, Dept Internal Med, Hypertens Div, Ljubljana, Slovenia

[5] Hop St Andre, Dept Cardiol, Hypertens Unit, Bordeaux, France

[6] Univ Hosp Bordeaux, Bordeaux, France

[7] Hosp 12 Octubre, Dept Nephrol, Hypertens Unit, Madrid, Spain

[8] Saarland Univ, Dept Internal Med Cardiol Angiol & Intens Care Me, Homburg, Germany

[9] Catholic Univ Louvain, Clin Univ St Luc, Div Cardiol, Brussels, Belgium

[10] Catholic Univ Louvain, Inst Rech Expt & Clin, Pole Cardiovasc Res, Brussels, Belgium

[11] Karolinska Inst, Danderyd Hosp, Dept Clin Sci, Div Cardiovasc Med, Stockholm, Sweden

[12] Univ Brescia, Dept Clin & Expt Sci, Clin Med Gen, Brescia, Italy

[13] Azienda Spedali Civili Brescia, Dept Med, Brescia, Italy

[14] Federico II Univ Hosp, Dept Translat Med Sci, Hypertens Res Ctr, Naples, Italy

[15] UCL, London, England

[16] UCL Hosp, London, England

来源：

EUROPEAN HEART JOURNAL-CARDIOVASCULAR PHARMACOTHERAPY | 2019年 / 5卷 / 01期

基金：

英国医学研究理事会;

关键词：

Hypertensive crisis; Hypertensive emergency; Malignant hypertension; Hypertensive urgency; Hypertensive encephalopathy; INDUCED CORONARY VASOCONSTRICTION; MALIGNANT HYPERTENSION; BLOOD-PRESSURE; SODIUM-NITROPRUSSIDE; ENDOTHELIAL DYSFUNCTION; MYOCARDIAL-INFARCTION; ADRENERGIC-BLOCKADE; PLATELET ACTIVATION; MANAGEMENT; LABETALOL;

D O I：

10.1093/ehjcvp/pvy032

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Hypertensive emergencies are those situations where very high blood pressure (BP) values are associated with acute organ damage, and therefore, require immediate, but careful, BP reduction. The type of acute organ damage is the principal determinant of: (i) the drug of choice, (ii) the target BP, and (iii) the timeframe in which BP should be lowered. Key target organs are the heart, retina, brain, kidneys, and large arteries. Patients who lack acute hypertension-mediated end organ damage do not have a hypertensive emergency and can usually be treated with oral BP-lowering agents and usually discharged after a brief period of observation.

引用

页码：37 / 46

页数：10

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