Plasmodium falciparum and Dihydrofolate Reductase I164L Mutations in Africa

被引：1
作者：
Alker, Alisa P.
Juliano, Jonathan J.
Meshnick, Steven R. [1 ]
机构：
[1] Univ N Carolina, Sch Med, Chapel Hill, NC 27599 USA
来源：
ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2009年 / 53卷 / 04期
关键词：
SULFADOXINE-PYRIMETHAMINE; DRUG-RESISTANCE; MALAWI; UGANDA; ASSAY;
D O I：
10.1128/AAC.01427-08
中图分类号：
Q93 [微生物学];
学科分类号：
071005 ; 100705 ;
摘要：
引用
收藏
页码：1722 / 1722
页数：1
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共 8 条
  • [1] Mutations associated with Sulfadoxine-pyrimethamine and chlorproguanil resistance in Plasmodium falciparum isolates from Blantyre, Malawi
    Alker, AP
    Mwapasa, V
    Purfield, A
    Rogerson, SJ
    Molyneux, ME
    Kamwendo, DD
    Tadesse, E
    Chaluluka, E
    Meshnick, SR
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2005, 49 (09) : 3919 - 3921
  • [2] Rapid real-time PCR genotyping of mutations associated with sulfadoxine-pyrimethamine resistance in Plasmodium falciparum
    Alker, AP
    Mwapasa, V
    Meshnick, SR
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2004, 48 (08) : 2924 - 2929
  • [3] Geographic differences in antimalarial drug efficacy in Uganda are explained by differences in endemicity and not by known molecular markers of drug resistance
    Francis, D
    Nsobya, SL
    Talisuna, A
    Yeka, A
    Kamya, MR
    Machekano, R
    Dokomajilar, C
    Rosenthal, PJ
    Dorsey, G
    [J]. JOURNAL OF INFECTIOUS DISEASES, 2006, 193 (07) : 978 - 986
  • [4] Short report:: Detection of the dihydrofolate reductase-164L mutation in Plasmodium falciparum infections from Malawi by heteroduplex tracking assay
    Juliano, Jonathan J.
    Trottman, Paul
    Mwapasa, Victor
    Meshnick, Steven R.
    [J]. AMERICAN JOURNAL OF TROPICAL MEDICINE AND HYGIENE, 2008, 78 (06) : 892 - 894
  • [5] Allelic discrimination using fluorogenic probes and the 5′ nuclease assay
    Livak, KJ
    [J]. GENETIC ANALYSIS-BIOMOLECULAR ENGINEERING, 1999, 14 (5-6): : 143 - 149
  • [6] Emergence of a dhfr mutation conferring high-level drug resistance in Plasmodium falciparum populations from southwest Uganda
    Lynch, Caroline
    Pearce, Richard
    Pota, Hirva
    Cox, Jonathan
    Abeku, Tarekegn A.
    Rwakimari, John
    Naidoo, Inbarani
    Tibenderana, James
    Roper, Cally
    [J]. JOURNAL OF INFECTIOUS DISEASES, 2008, 197 (11) : 1598 - U66
  • [7] Plasmodium falciparum Strains Harboring Dihydrofolate Reductase with the I164L Mutation Are Absent in Malawi and Zambia Even under Antifolate Drug Pressure
    Ochong, Edwin
    Bell, David J.
    Johnson, David J.
    D'Alessandro, Umberto
    Mulenga, Modest
    Muangnoicharoen, Sant
    Van Geertruyden, Jean-Pierre
    Winstanley, Peter A.
    Bray, Patrick G.
    Ward, Stephen A.
    Owen, Andrew
    [J]. ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2008, 52 (11) : 3883 - 3888
  • [8] Mutation rates in the dihydrofolate reductase gene of Plasmodium falciparum
    Paget-McNicol, S
    Saul, A
    [J]. PARASITOLOGY, 2001, 122 : 497 - 505
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