Repolarization Heterogeneity of Magnetocardiography Predicts Long-Term Prognosis in Patients with Acute Myocardial Infarction

被引:13
作者
Bang, Woo-Dae [1 ,2 ]
Kim, Kiwoong [3 ]
Lee, Yong-Ho [3 ]
Kwon, Hyukchan [3 ]
Park, Yongki [3 ]
Pak, Hui-Nam [1 ]
Ko, Young-Guk [1 ]
Lee, Moonhyoung [1 ]
Joung, Boyoung [1 ]
机构
[1] Yonsei Univ, Coll Med, Dept Internal Med, Div Cardiol, 50-1 Yonsei Ro, Seoul 03722, South Korea
[2] Univ Ulsan, Gangneung Asan Hosp, Coll Med, Dept Cardiol, Kangnung, South Korea
[3] Korea Res Inst Stand & Sci, Biosignal Res Ctr, Daejeon, South Korea
基金
新加坡国家研究基金会;
关键词
Acute myocardial infarction; prognosis; magnetocardiography; PERCUTANEOUS CORONARY INTERVENTION; TROPONIN-T; RISK; ELECTROCARDIOGRAM; MORTALITY;
D O I
10.3349/ymj.2016.57.6.1339
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Purpose: Magnetocardiography (MCG) has been proposed as a noninvasive, diagnostic tool for risk-stratifying patients with acute myocardial infarction (AMI). This study evaluated whether MCG predicts long-term prognosis in AMI. Meterials and Methods: In 124 AMI patients (95 males, mean age 60 +/- 11 years), including 39 with ST-elevation myocardial infarction, a 64-channel MCG was performed within 2 days after AMI. During a mean follow-up period of 6.1 years, major adverse cardiac events (MACE) were evaluated. Results: MACE occurred in 31 (25%) patients, including 20 revascularizations, 8 deaths, and 3 re-infarctions. Non-dipole patterns were observed at the end of the T wave in every patients. However, they were observed at T-peak in 77% (24/31) and 54% (50/93) of patients with and without MACE, respectively (p=0.03). Maximum current, field map angles, and distance dynamics were not different between groups. In the multivariate analysis, patients with non-dipole patterns at T-peak had increased age- and gender-adjusted hazard ratios for MACE (hazard ratio 2.89, 95% confidence interval 1.20-6.97, p=0.02) and lower cumulative MACE-free survival than those with dipole patterns (p=0.02). Conclusion: Non-dipole patterns at T-peak were more frequently observed in patients with MACE and were related to poor long-term prognosis. Thus, repolarization heterogeneity measured by MCG may be a useful predictor for AMI prognosis.
引用
收藏
页码:1339 / 1346
页数:8
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