Severe Sepsis and Septic Shock

被引：2190

作者：

Calis, Job ^{[1
]}

van Woensel, Job ^{[1
]}

Lemson, Joris ^{[2
]}

机构：

[1] Univ Amsterdam, Acad Med Ctr, NL-1105 AZ Amsterdam, Netherlands

[2] Radboud Univ Nijmegen, Med Ctr, NL-6525 ED Nijmegen, Netherlands

来源：

NEW ENGLAND JOURNAL OF MEDICINE | 2013年 / 369卷 / 21期

关键词：

D O I：

10.1056/NEJMc1312359

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

To the Editor: We would like to address two potentially confusing issues concerning venous oxygen saturation (Svo(2)) as presented in Table 1 of the review by Angus and van der Poll (Aug. 29 issue).(1) First, Table 1 suggests that Svo(2) is raised in sepsis, severe sepsis, and septic shock. Depending on the timing of patient presentation and the type of sepsis and septic shock, Svo(2) may indeed be elevated as a result of microcirculatory shunting or mitochondrial dysfunction. However, in septic shock, Svo(2) can be depressed, reflecting an increase in the extraction of oxygen due ...

引用

页码：2062 / 2062

页数：1

共 11 条

[1] Severe Sepsis and Septic Shock [J].

Calis, Job ;

van Woensel, Job ;

Lemson, Joris .

NEW ENGLAND JOURNAL OF MEDICINE, 2013, 369 (21) :2062-2062

[2] Immature platelet fraction in predicting sepsis in critically ill patients [J].

De Blasi, Roberto Alberto ;

Cardelli, Patrizia ;

Costante, Alessandro ;

Sandri, Micol ;

Mercieri, Marco ;

Arcioni, Roberto .

INTENSIVE CARE MEDICINE, 2013, 39 (04) :636-643

[3] ACCM/PALS haemodynamic support guidelines for paediatric septic shock: an outcomes comparison with and without monitoring central venous oxygen saturation [J].

de Oliveira, Claudio F. ;

de Oliveira, Debora S. F. ;

Gottschald, Adriana F. C. ;

Moura, Juliana D. G. ;

Costa, Graziela A. ;

Ventura, Andrea C. ;

Fernandes, Jose Carlos ;

Vaz, Flavio A. C. ;

Carcillo, Joseph A. ;

Rivers, Emanuel P. ;

Troster, Eduardo J. .

INTENSIVE CARE MEDICINE, 2008, 34 (06) :1065-1075

[4] Evolution of haemodynamics and outcome of fluid-refractory septic shock in children [J].

Deep, Akash ;

Goonasekera, Chulananda D. A. ;

Wang, Yanzhong ;

Brierley, Joe .

INTENSIVE CARE MEDICINE, 2013, 39 (09) :1602-1609

[5]

Dellinger RP, 2013, INTENS CARE MED, V39, P165, DOI [10.1097/CCM.0b013e31827e83af, 10.1007/s00134-012-2769-8]

[6] Immature platelet fraction (IPF) in hospitalized patients with neutrophilia and suspected bacterial infection [J].

Di Mario, Antonella ;

Garzia, Mariagrazia ;

Leone, Fiammetta ;

Arcangeli, Andrea ;

Pagano, Livio ;

Zini, Gina .

JOURNAL OF INFECTION, 2009, 59 (03) :201-206

[7] Critical Care of Persons Infected with the Human Immunodeficiency Virus [J].

Ganesan, Anuradha ;

Masur, Henry .

CLINICS IN CHEST MEDICINE, 2013, 34 (02) :307-+

[8] Sepsis is a major determinant of outcome in critically ill HIV/AIDS patients [J].

Japiassu, Andre M. ;

Amancio, Rodrigo T. ;

Mesquita, Emerson C. ;

Medeiros, Denise M. ;

Bernal, Helena B. ;

Nunes, Estevao P. ;

Luz, Paula M. ;

Grinsztejn, Beatriz ;

Bozza, Fernando A. .

CRITICAL CARE, 2010, 14 (04)

[9] Early goal-directed therapy in the treatment of severe sepsis and septic shock. [J].

Rivers, E ;

Nguyen, B ;

Havstad, S ;

Ressler, J ;

Muzzin, A ;

Knoblich, B ;

Peterson, E ;

Tomlanovich, M .

NEW ENGLAND JOURNAL OF MEDICINE, 2001, 345 (19) :1368-1377

[10] Sepsis in AIDS patients: clinical, etiological and inflammatory characteristics [J].

Silva, Joao Manoel, Jr. ;

dos Santos, Sigrid De Sousa .

JOURNAL OF THE INTERNATIONAL AIDS SOCIETY, 2013, 16

← 1 2 →