Transcriptomic basis of sex loss in the pea aphid

被引：2

作者：

Huguet, M. D. ^{[1
]}

Robin, S. ^{[1
,2
]}

Hudaverdian, S. ^{[1
]}

Tanguy, S. ^{[1
]}

Leterme-Prunier, N. ^{[1
]}

Cloteau, R. ^{[1
]}

Baulande, S. ^{[3
]}

Legoix-Ne, P. ^{[3
]}

Legeai, F. ^{[1
,2
]}

Simon, J. -C. ^{[1
]}

Jaquiery, J. ^{[1
]}

Tagu, D. ^{[1
]}

Le Trionnaire, G. ^{[1
]}

机构：

[1] Univ Rennes, Inst Genet Environm & Plant Protect, Inst Agro, IGEPP,INRAE, F-35653 Le Rheu, France

[2] Inst Natl Rech Informat & Automat, Inst Rech Informat & Syst Aleatoires, Genscale, Campus Beaulieu, F-35042 Rennes, France

[3] PSL Res Univ, Inst Curie, Ctr Rech, Genom Excellence Platform, Paris, France

来源：

BMC GENOMICS | 2024年 / 25卷 / 01期

关键词：

Cyclical and obligate parthenogenesis; Gene expression; Reproductive polymorphism; Asexuality; Insects; JUVENILE-HORMONE; GENE-EXPRESSION; PARTHENOGENESIS; LOCALIZATION; EVOLUTION; PHOTOPERIODISM; PERSPECTIVE; BIOGENESIS;

D O I：

10.1186/s12864-023-09776-6

中图分类号：

Q81 [生物工程学（生物技术）]; Q93 [微生物学];

学科分类号：

071005 ; 0836 ; 090102 ; 100705 ;

摘要：

BackgroundTransitions from sexual to asexual reproduction are common in eukaryotes, but the underlying mechanisms remain poorly known. The pea aphid-Acyrthosiphon pisum-exhibits reproductive polymorphism, with cyclical parthenogenetic and obligate parthenogenetic lineages, offering an opportunity to decipher the genetic basis of sex loss. Previous work on this species identified a single 840 kb region controlling reproductive polymorphism and carrying 32 genes. With the aim of identifying the gene(s) responsible for sex loss and the resulting consequences on the genetic programs controlling sexual or asexual embryogenesis, we compared the transcriptomic response to photoperiod shortening-the main sex-inducing cue-of a sexual and an obligate asexual lineage of the pea aphid, focusing on heads (where the photoperiodic cue is detected) and embryos (the final target of the cue).ResultsOur analyses revealed that four genes (one expressed in the head, and three in the embryos) of the region responded differently to photoperiod in the two lineages. We also found that the downstream genetic programs expressed during embryonic development of a future sexual female encompass similar to 1600 genes, among which miRNAs, piRNAs and histone modification pathways are overrepresented. These genes mainly co-localize in two genomic regions enriched in transposable elements (TEs).ConclusionsOur results suggest that the causal polymorphism(s) in the 840 kb region somehow impair downstream epigenetic and post-transcriptional regulations in obligate asexual lineages, thereby sustaining asexual reproduction.

引用

页数：17

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