Diagnostic Value of Adding Magnifying Chromoendoscopy to Magnifying Narrow-Band Imaging Endoscopy for Colorectal Polyps

被引：6

作者：

Matsumura, Tomoaki ^{[1
,12
]}

Ebigbo, Alanna ^{[2
]}

Roemmele, Christoph ^{[2
]}

Ikematsu, Hiroaki ^{[3
]}

Ishigami, Hideaki ^{[4
]}

Suzuki, Takuto ^{[5
]}

Harada, Hideaki ^{[6
]}

Yada, Tomoyuki ^{[7
]}

Takatori, Yusaku ^{[8
]}

Takeuchi, Manabu ^{[9
]}

Okimoto, Kenichiro ^{[1
]}

Akizue, Naoki ^{[1
]}

Maruoka, Daisuke ^{[1
]}

Kitagawa, Yoshiyasu ^{[5
]}

Minamide, Tatsunori ^{[3
]}

Iwaki, Tomoyuki ^{[6
]}

Amano, Yuji ^{[6
]}

Matsusaka, Keisuke ^{[10
]}

Nagashima, Kengo ^{[11
]}

Maehata, Tadateru ^{[8
]}

Yahagi, Naohisa ^{[8
]}

Messmann, Helmut ^{[2
]}

Kato, Naoya ^{[1
]}

机构：

[1] Chiba Univ, Grad Sch Med, Dept Gastroenterol, Chiba, Japan

[2] Universitatsklinikum Augsburg, Dept Gastroenterol, Augsburg, Germany

[3] Natl Canc Ctr Hosp East, Div Endoscopy & Gastrointestinal Oncol, Chiba, Japan

[4] Chiba Rosai Hosp, Dept Gastroenterol, Chiba, Japan

[5] Chiba Canc Ctr, Endoscopy Div, Chiba, Japan

[6] New Tokyo Hosp, Dept Gastroenterol, Chiba, Japan

[7] Kohnodai Hosp, Natl Ctr Global Hlth & Med, Div Gastroenterol & Hepatol, Chiba, Japan

[8] Keio Univ, Sch Med, Canc Ctr, Div Res & Dev Minimally Invas Treatment, Tokyo, Japan

[9] Nagaoka Red Cross Hosp, Div Gastroenterol & Hepatol, Nagaoka, Japan

[10] Chiba Univ Hosp, Dept Pathol, Chiba, Japan

[11] Keio Univ Hosp, Clin & Translat Res Ctr, Biostat Unit, Tokyo, Japan

[12] Chiba Univ, Grad Sch Med, Dept Gastroenterol, Inohana 1-8-1, Chiba 2608670, Japan

来源：

CLINICAL GASTROENTEROLOGY AND HEPATOLOGY | 2023年 / 21卷 / 10期

关键词：

Colorectal Polyp; Colorectal Cancer; Chromoendoscopy; Narrow-Band Imaging; Optical Diagnosis; INVASION DEPTH; CANCER; ACCURACY; TUMORS; CLASSIFICATION; POLYPECTOMY; NEOPLASIA; PATTERN; LESIONS;

D O I：

10.1016/j.cgh.2023.01.028

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

BACKGROUND & AIMS: This study examined the additional value of magnifying chromoendoscopy (MCE) on magnifying narrow-band imaging endoscopy (M-NBI) in the optical diagnosis of colorectal polyps. METHODS: A multicenter prospective study was conducted at 9 facilities in Japan and Germany. Patients with colorectal polyps scheduled for resection were included. Optical diagnosis was performed by M-NBI first, followed by MCE. Both diagnoses were made in real time. MCE was performed on all type 2B lesions classified according to the Japan NBI Expert Team classification and other lesions at the discretion of endoscopists. The diagnostic accuracy and confidence of M-NBI and MCE for colorectal cancer (CRC) with deep invasion (>= T1b) were compared on the basis of histologic findings after resection. RESULTS: In total, 1173 lesions were included between February 2018 and December 2020, with 654 (5 hyperplastic polyp/sessile serrated lesion, 162 low-grade dysplasia, 403 high-grade dysplasia, 97 T1 CRCs, and 32 >= T2 CRCs) examined using MCE after M-NBI. In the diagnostic accuracy for predicting CRC with deep invasion, sensitivity, specificity, positive predictive value, negative predictive value, and accuracy for M-NBI were 63.1%, 94.2%, 61.6%, 94.5%, and 90.2%, respectively, and for MCE they were 77.4%, 93.2%, 62.5%, 96.5%, and 91.1%, respectively. The sensitivity was significantly higher in MCE (P <.001). However, these additional values were limited to lesions with low confidence in M-NBI or the ones diagnosed as >= T1b CRC by M-NBI. CONCLUSIONS: In this multicenter prospective study, we demonstrated the additional value of MCE on M-NBI. We suggest that additional MCE be recommended for lesions with low confidence or the ones diagnosed as >= T1b CRC. Trials registry number: UMIN000031129.

引用

页码：2551 / +

页数：11

共 29 条

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