The Italian Society of Andrology and Sexual Medicine (SIAMS), along with ten other Italian Scientific Societies, guidelines on the diagnosis and management of erectile dysfunction

被引:64
作者
Corona, G. [1 ]
Cucinotta, D. [2 ]
Di Lorenzo, G. [3 ,4 ]
Ferlin, A. [5 ]
Giagulli, V. A. [6 ,7 ]
Gnessi, L. [8 ]
Isidori, A. M. [9 ]
Maiorino, M. I. [10 ]
Miserendino, P. [11 ]
Murrone, A. [12 ]
Pivonello, R. [13 ,14 ]
Rochira, V. [15 ]
Sangiorgi, G. M. [16 ]
Stagno, G. [17 ]
Foresta, C. [5 ]
Lenzi, A. [8 ]
Maggi, M. [18 ]
Jannini, E. A. [19 ]
机构
[1] Maggiore Bellaria Hosp, Med Dept, Endocrinol Unit, Azienda Usl, Bologna, Italy
[2] Univ Messina, Chair Internal Med, Dept Clin & Expt Med, Messina, Italy
[3] Univ Roma Tor Vergata, Dept Syst Med, Sect Psychiat, Rome, Italy
[4] IRCCS Fdn Santa Lucia, Rome, Italy
[5] Univ Padua, Dept Med, Unit Androl & Reprod Med, Padua, Italy
[6] Univ Bari Aldo Moro, Interdisciplinary Dept Med, Sect Internal Med Geriatr Endocrinol & Rare Dis, Bari, Italy
[7] Santa Maria Hosp, GVM Care & Res, Bari, Italy
[8] Sapienza Univ Rome, Dept Expt Med, Sect Food Sci, Rome, Italy
[9] Sapienza Univ Rome, Dept Expt Med, Sect Endocrinol, Rome, Italy
[10] Univ Campania Luigi Vanvitelli, Dept Adv Med & Surg Sci, Div Endocrinol & Metab Dis, Naples, Italy
[11] ASP, Diabetol & Endocrinol Unit, Caltanissetta, Italy
[12] Azienda Usl Umbria 1, Citta Castello & Gubbio GualdoTadino Hosp, Cardiol Unit, Gubbio, Italy
[13] Univ Federico II Napoli, Dipartimento Med Clin & Chirurg, Unita Androl & Med Riproduz & Sessual Maschile & F, Sez Endocrinol, Naples, Italy
[14] Univ Naples Federico II, Staff UNESCO Chair Hlth Educ & Sustainable Dev, Naples, Italy
[15] Univ Modena & Reggio Emilia, Dept Biomed Metab & Neural Sci, Modena, Italy
[16] Policlin Tor Vergata, Dept Biomed & Prevent, Rome, Italy
[17] ASP Reggio Calabria, Diabetol Unit, Reggio Di Calabria, Italy
[18] Univ Florence, Dept Expt Clin & Biomed Sci, Endocrinol Unit, Florence, Italy
[19] Univ Roma Tor Vergata, Chair Endocrinol & Sexual Med ENDOSEX, Dept Syst Med, Tower South Floor 4,Room E413,Via Montpellier 1, I-00133 Rome, Italy
关键词
Erectile dysfunction; Premature ejaculation; Sexual desire; Obesity; Testosterone; Phosphodiesterase type 5 inhibitors; 4TH INTERNATIONAL CONSULTATION; ASSISTED RADICAL PROSTATECTOMY; ADVERSE CARDIOVASCULAR EVENTS; COGNITIVE-BEHAVIORAL THERAPY; BENIGN PROSTATIC HYPERPLASIA; LATE-ONSET HYPOGONADISM; LIFE-STYLE CHANGES; PREMATURE EJACULATION; INHIBITORS; DEPRESSIVE SYMPTOMS;
D O I
10.1007/s40618-023-02015-5
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
PurposeErectile dysfunction (ED) is one of the most prevalent male sexual dysfunctions. ED has been in the past mistakenly considered a purely psycho-sexological symptom by patients and doctors. However, an ever-growing body of evidence supporting the role of several organic factors in the pathophysiological mechanisms underlying ED has been recognized.MethodsThe Italian Society of Andrology and Sexual Medicine (SIAMS) commissioned an expert task force involving several other National Societies to provide an updated guideline on the diagnosis and management of ED. Derived recommendations were based on the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) system.ResultsSeveral evidence-based statements were released providing the necessary up-to-date guidance in the context of ED with organic and psychosexual comorbidities. Many of them were related to incorrect lifestyle habits suggesting how to associate pharmacotherapies and counseling, in a couple-centered approach. Having the oral therapy with phosphodiesterase type 5 inhibitors as the gold standard along with several other medical and surgical therapies, new therapeutic or controversial options were also discussed.ConclusionsThese are the first guidelines based on a multidisciplinary approach that involves the most important Societies related to the field of sexual medicine. This fruitful discussion allowed for a general agreement on several recommendations and suggestions to be reached, which can support all stakeholders in improving couple sexual satisfaction and overall general health.
引用
收藏
页码:1241 / 1274
页数:34
相关论文
共 294 条
[1]   Health-Related Lifestyle Factors and Sexual Dysfunction: A Meta-Analysis of Population-Based Research [J].
Allen, Mark S. ;
Walter, Emma E. .
JOURNAL OF SEXUAL MEDICINE, 2018, 15 (04) :458-475
[2]   The pathophysiology of cigarette C-V smoking and cardiovascular disease - An update [J].
Ambrose, JA ;
Barua, RS .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2004, 43 (10) :1731-1737
[3]   Rigiscan Evaluation of Men with Diabetes Mellitus and Erectile Dysfunction and Correlation with Diabetes Duration, Age, BMI, Lipids and HbA1c [J].
Andersson, Daniel Peter ;
Ekstrom, Urban ;
Lehtihet, Mikael .
PLOS ONE, 2015, 10 (07)
[4]  
[Anonymous], 1993, JAMA-J AM MED ASSOC, V270, P83, DOI DOI 10.1001/JAMA.1993.03510010089036
[5]   Low Free Testosterone Is Associated with Hypogonadal Signs and Symptoms in Men with Normal Total Testosterone [J].
Antonio, Leen ;
Wu, Frederick C. W. ;
O'Neill, Terence W. ;
Pye, Stephen R. ;
Ahern, Tomas B. ;
Laurent, Michael R. ;
Huhtaniemi, Ilpo T. ;
Lean, Michael E. J. ;
Keevil, Brian G. ;
Rastrelli, Giulia ;
Forti, Gianni ;
Bartfai, Gyorgy ;
Casanueva, Felipe F. ;
Kula, Krzysztof ;
Punab, Margus ;
Giwercman, Aleksander ;
Claessens, Frank ;
Decallonne, Brigitte ;
Vanderschueren, Dirk .
JOURNAL OF CLINICAL ENDOCRINOLOGY & METABOLISM, 2016, 101 (07) :2647-2657
[6]   Salvage of sildenafil failures referred from primary care physicians [J].
Atiemo, HO ;
Szostak, MJ ;
Sklar, GN .
JOURNAL OF UROLOGY, 2003, 170 (06) :2356-2358
[7]   Sexual symptoms in endocrine diseases: Psychosomatic perspectives [J].
Balercia, Giancarlo ;
Boscaro, Marco ;
Lombardo, Francesco ;
Carosa, Eleonora ;
Lenzi, Andrea ;
Jannini, Emmanuele A. .
PSYCHOTHERAPY AND PSYCHOSOMATICS, 2007, 76 (03) :134-140
[8]   Severe Depressive Symptoms and Cardiovascular Risk in Subjects with Erectile Dysfunction [J].
Bandini, Elisa ;
Fisher, Alessandra D. ;
Corona, Giovanni ;
Ricca, Valdo ;
Monami, Matteo ;
Boddi, Valentina ;
Balzi, Daniela ;
Melani, Cecilia ;
Forti, Gianni ;
Mannucci, Edoardo ;
Maggi, Mario .
JOURNAL OF SEXUAL MEDICINE, 2010, 7 (10) :3477-3486
[9]   Erectile Dysfunction and Premature Ejaculation in Homosexual and Heterosexual Men: A Systematic Review and Meta-Analysis of Comparative Studies [J].
Barbonetti, Arcangelo ;
D'Andrea, Settimio ;
Cavallo, Francesca ;
Martorella, Alessio ;
Francavilla, Sandro ;
Francavilla, Felice .
JOURNAL OF SEXUAL MEDICINE, 2019, 16 (05) :624-632
[10]   2018 ACC Expert Consensus Decision Pathway on Tobacco Cessation Treatment A Report of the American College of Cardiology Task Force on Clinical Expert Consensus Documents [J].
Barua, Rajat S. ;
Rigotti, Nancy A. ;
Benowitz, Neal L. ;
Cummings, K. Michael ;
Jazayeri, Mohammad-Ali ;
Morris, Pamela B. ;
Ratchford, Elizabeth V. ;
Sarna, Linda ;
Stecker, Eric C. ;
Wiggins, Barbara S. ;
Januzzi, James L. ;
Ahmad, Tariq ;
Everett, Brendan ;
Hucker, William ;
Kumbhani, Dharam J. ;
Marine, Joseph E. ;
Morris, Pamela B. ;
Piana, Robert N. ;
Rao, Sunil V. ;
Scherrer-Crosbie, Marielle ;
Watson, Karol E. ;
Wiggins, Barbara S. .
JOURNAL OF THE AMERICAN COLLEGE OF CARDIOLOGY, 2018, 72 (25) :3332-3365