Application of the aza-Wittig reaction for efficient synthesis of diversely substituted benzo[f]Chromeno[2,3-d]pyrimidine and benzo[f]chromeno[2,3-d][1,2,4]triazolopyrimidine derivatives

被引:1
作者
Hassan, Mohamed [1 ]
Barsy, Magda A. [1 ]
El Rady, Eman A. [1 ]
Al-Ayed, Abdullah Sulaiman [2 ]
Frempong, Mona [3 ]
Sadek, Kamal U. [4 ]
机构
[1] Aswan Univ, Fac Sci, Dept Chem, Aswan 81528, Egypt
[2] Qassim Univ, Coll Sci & Arts, Dept Chem, Ar Rass, Saudi Arabia
[3] Ctr Dis Control & Prevent, Atlanta, GA USA
[4] Minia Univ, Fac Sci, Chem Dept, Al Minya, Egypt
关键词
ONE-POT SYNTHESIS; IN-VITRO; ANTITUMOR; DESIGN;
D O I
10.1002/jhet.4784
中图分类号
O62 [有机化学];
学科分类号
070303 ; 081704 ;
摘要
An efficient synthesis of novel benzo[f]Chromeno[2,3-d]pyrimidine and unknown benzo[f]chromeno[2,3-d][1,2,4]triazolopyrimidine derivatives is described utilizing ethyl-2-amino-4-phenyl-4H-benzo[f]chromene-3-carboxyl-ate as precursor via aza-Wittig reaction. The process proved to be simple, high yielding, and efficient.
引用
收藏
页码:543 / 549
页数:7
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