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- [7] Apoptosis of antigen-specific T lymphocytes upon the engagement of CD8 by soluble HLA class I molecules is Fas ligand/Fas mediated:: Evidence for the involvement of p56lck calcium calmodulin kinase II, and calcium-independent protein kinase C signaling pathways and for NF-κB and NF-AT nuclear translocation JOURNAL OF IMMUNOLOGY, 2005, 175 (11): : 7244 - 7254