Refractory Cytomegalovirus Colitis Followed by De Novo Inflammatory Bowel Disease Post-Orthotopic Liver Transplantation

被引：0

作者：

Selvan, Bharathi ^{[1
]}

Pendse, Avani A. ^{[2
]}

Zhang, Cecelia ^{[3
]}

Cauthen, Jeffriann ^{[3
]}

Kappus, Matthew R. ^{[3
]}

Messina, Julia A. ^{[4
]}

机构：

[1] Duke Univ, Sch Med, Durham, NC 27708 USA

[2] Duke Univ, Sch Med, Dept Pathol, Durham, NC USA

[3] Duke Univ, Sch Med, Dept Med, Div Gastroenterol, Durham, NC USA

[4] Duke Univ, Sch Med, Dept Med, Div Infect Dis, Durham, NC USA

来源：

ACG CASE REPORTS JOURNAL | 2023年 / 10卷 / 12期

关键词：

cytomegalovirus; inflammatory bowel disease; liver transplantation; ULCERATIVE-COLITIS; INFECTION;

D O I：

10.14309/crj.0000000000001232

中图分类号：

R57 [消化系及腹部疾病];

学科分类号：

摘要：

Cytomegalovirus (CMV) and inflammatory bowel disease (IBD) are both immune-mediated complications that affect orthotopic liver transplantation patients. In this report, we present a 60-year-old man who underwent orthotopic liver transplantation for cryptogenic cirrhosis with serologies notable for CMV-seropositive donor and seronegative recipient. His post-transplant course was initially complicated by probable refractory CMV colitis. However, his gastrointestinal symptoms persisted, eventually leading to a diagnosis of post-transplant de novo IBD. The discussion highlights theories regarding the association between CMV and IBD, a topic that has been widely debated for decades.

引用

页数：4

共 20 条

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