Heparin Concentration in Evacuated Tubes and Its Effect on pH, Ionized Calcium, Lactate, and Potassium in Venous Blood Gas Analysis

被引：2

作者：

Mahler, Katherine ^{[1
]}

Kerlin, Rae ^{[1
]}

Jones, Joanna ^{[2
]}

Li, Jieli ^{[2
]}

机构：

[1] Univ Hosp, Dept Clin Lab, Columbus, OH USA

[2] Ohio State Univ, Dept Pathol, Wexner Med Ctr, Columbus, OH 43210 USA

来源：

LABORATORY MEDICINE | 2023年 / 54卷 / 05期

关键词：

lithium heparin; sodium heparin; venous blood gas; ionized calcium; pH; evacuated tubes;

D O I：

10.1093/labmed/lmad022

中图分类号：

R446 [实验室诊断]; R-33 [实验医学、医学实验];

学科分类号：

1001 ;

摘要：

Arterial blood specimens collected in evacuated tubes are unacceptable for blood gas analysis. However, evacuated tubes are routinely used for venous blood-gas analysis. The impact of the blood to heparin ratio on venous blood in evacuated tubes is unclear. Venous blood was drawn into lithium and sodium heparin evacuated tubes that were 1/3 full, 1/2 full, 2/3 full, and fully filled. Specimens were analyzed for pH, ionized calcium (iCa), lactate, and potassium on a blood-gas analyzer. The results for specimens filled only 1/3 full for lithium and sodium heparin tubes revealed a significant increase in pH and a significant decrease in the iCa. Underfilling the lithium and sodium heparin evacuated tubes did not significantly impact the lactate or potassium results. Venous whole-blood specimens should be filled to at least 2/3 full for accurate pH and iCa results.

引用

页码：E157 / E160

页数：4

共 5 条

[1] Errors in a stat laboratory: Types and frequencies 10 years later [J].