Orthostatic Hypotension in Benign Prostatic Hyperplasia Patients and Its Association With Alpha-1 Antagonist Use: A Comprehensive Literature Review

被引：1

作者：

Abubakar, Muhammad ^{[1
,2
]}

Prasad, Rachna ^{[3
]}

Salim, Siffat S. ^{[4
]}

Basavaraju, Deepak ^{[5
]}

Khan, Munazza ^{[6
]}

Lateef, Ibrahim K. ^{[6
]}

Furqan, Ahmad ^{[7
]}

Raza, Saud ^{[2
]}

Gupta, Ishita ^{[8
]}

Singla, Deepak ^{[9
]}

Adil, Hira ^{[10
]}

Naeem, Ather ^{[11
]}

机构：

[1] Sidd Sadiq Mem Trust Hosp, Dept Internal Med, Gujranwala, Pakistan

[2] Lahore Gen Hosp, Ameer ud Din Med Coll, Dept Internal Med, Lahore, Pakistan

[3] Stanley Med Coll, Dept Internal Med, Chennai, India

[4] Holy Family Red Crescent Med Coll Hosp, Dept Surg, Dhaka, Bangladesh

[5] Mysore Med Coll & Res Inst, Dept Internal Med, Mysore, India

[6] Med Univ Pleven, Dept Internal Med, Pleven, Bulgaria

[7] Shalamar Med & Dent Coll, Dept Internal Med, Lahore, Pakistan

[8] Dr Baba Saheb Ambedkar Med Coll & Hosp, Dept Internal Med, New Delhi, India

[9] Govt Med Coll, Dept Internal Med, Patiala, India

[10] Khyber Girls Med Coll, Dept Community Med, Peshawar, Pakistan

[11] Punjab Inst Cardiol, Dept Cardiol, Lahore, Pakistan

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2023年 / 15卷 / 08期

关键词：

quality of life; orthostatic hypotension; lower urinary tract symptoms; benign prostatic hyperplasia; alpha-1 adrenergic antagonists; URINARY-TRACT SYMPTOMS; POOLED ANALYSIS; TAMSULOSIN; EFFICACY; ALFUZOSIN; SAFETY; SILODOSIN; PLACEBO; DIAGNOSIS; RECEPTOR;

D O I：

10.7759/cureus.44097

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Orthostatic hypotension (OH) is frequently observed in benign prostatic hyperplasia (BPH) patients undergoing alpha-1 adrenergic antagonist (A1AA) therapy. While previous studies have acknowledged the prevalence of OH in BPH patients on A1AAs, limited data exist on ranking the safety of different A1AAs. This comprehensive review explores the underlying mechanisms of OH, examines numerous factors influencing its development, and provides insights into effective treatment strategies such as hydration, gradual postural changes, leg exercises, compression stockings, and tilt-table training for BPH management. The review highlights the significance of individualized care, interdisciplinary collaboration, and further research to optimize A1AA treatment, improve patient outcomes, and enhance quality of life.

引用

页数：9

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