Orthostatic Hypotension in Benign Prostatic Hyperplasia Patients and Its Association With Alpha-1 Antagonist Use: A Comprehensive Literature Review

被引：1

作者：

Abubakar, Muhammad ^{[1
,2
]}

Prasad, Rachna ^{[3
]}

Salim, Siffat S. ^{[4
]}

Basavaraju, Deepak ^{[5
]}

Khan, Munazza ^{[6
]}

Lateef, Ibrahim K. ^{[6
]}

Furqan, Ahmad ^{[7
]}

Raza, Saud ^{[2
]}

Gupta, Ishita ^{[8
]}

Singla, Deepak ^{[9
]}

Adil, Hira ^{[10
]}

Naeem, Ather ^{[11
]}

机构：

[1] Sidd Sadiq Mem Trust Hosp, Dept Internal Med, Gujranwala, Pakistan

[2] Lahore Gen Hosp, Ameer ud Din Med Coll, Dept Internal Med, Lahore, Pakistan

[3] Stanley Med Coll, Dept Internal Med, Chennai, India

[4] Holy Family Red Crescent Med Coll Hosp, Dept Surg, Dhaka, Bangladesh

[5] Mysore Med Coll & Res Inst, Dept Internal Med, Mysore, India

[6] Med Univ Pleven, Dept Internal Med, Pleven, Bulgaria

[7] Shalamar Med & Dent Coll, Dept Internal Med, Lahore, Pakistan

[8] Dr Baba Saheb Ambedkar Med Coll & Hosp, Dept Internal Med, New Delhi, India

[9] Govt Med Coll, Dept Internal Med, Patiala, India

[10] Khyber Girls Med Coll, Dept Community Med, Peshawar, Pakistan

[11] Punjab Inst Cardiol, Dept Cardiol, Lahore, Pakistan

来源：

CUREUS JOURNAL OF MEDICAL SCIENCE | 2023年 / 15卷 / 08期

关键词：

quality of life; orthostatic hypotension; lower urinary tract symptoms; benign prostatic hyperplasia; alpha-1 adrenergic antagonists; URINARY-TRACT SYMPTOMS; POOLED ANALYSIS; TAMSULOSIN; EFFICACY; ALFUZOSIN; SAFETY; SILODOSIN; PLACEBO; DIAGNOSIS; RECEPTOR;

D O I：

10.7759/cureus.44097

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Orthostatic hypotension (OH) is frequently observed in benign prostatic hyperplasia (BPH) patients undergoing alpha-1 adrenergic antagonist (A1AA) therapy. While previous studies have acknowledged the prevalence of OH in BPH patients on A1AAs, limited data exist on ranking the safety of different A1AAs. This comprehensive review explores the underlying mechanisms of OH, examines numerous factors influencing its development, and provides insights into effective treatment strategies such as hydration, gradual postural changes, leg exercises, compression stockings, and tilt-table training for BPH management. The review highlights the significance of individualized care, interdisciplinary collaboration, and further research to optimize A1AA treatment, improve patient outcomes, and enhance quality of life.

引用

页数：9

共 67 条

[1] Updates in the function and regulation of α1-adrenoceptors [J].

Akinaga, Juliana ;

Adolfo Garcia-Sainz, J. ;

Pupo, Andre S. .

BRITISH JOURNAL OF PHARMACOLOGY, 2019, 176 (14) :2343-2357

[2]

[Anonymous], 2012, ALPH 1 ADR REC ANT

[3]

Biaggioni I, 2014, ENCY NEUROLOGICAL SC, VSecond, P698, DOI [10.1016/B978-0-12-385157-4.00507-8, DOI 10.1016/B978-0-12-385157-4.00507-8]

[4] Tamsulosin treatment for benign prostatic hyperplasia and risk of severe hypotension in men aged 40-85 years in the United States: risk window analyses using between and within patient methodology [J].

Bird, Steven T. ;

Delaney, Joseph A. C. ;

Brophy, James M. ;

Etminan, Mahyar ;

Skeldon, Sean C. ;

Hartzema, Abraham G. .

BMJ-BRITISH MEDICAL JOURNAL, 2013, 347

[5] Standing Up Slowly Antagonises Initial Blood Pressure Decrease in Older Adults with Orthostatic Hypotension [J].

Bruine, Eline S. Dde ;

Reijnierse, Esmee M. ;

Trappenburg, Marijke C. ;

Pasma, Jantsje H. ;

de Vries, Oscar J. ;

Meskers, Carel G. M. ;

Maier, Andrea B. .

GERONTOLOGY, 2017, 63 (02) :137-143

[6] Comparison of tamsulosin with alfuzosin in the treatment of patients with lower urinary tract symptoms suggestive of bladder outlet obstruction (symptomatic benign prostatic hyperplasia) [J].

Buzelin, JM ;

Fonteyne, E ;

Kontturi, M ;

Witjes, WPJ ;

Khan, A .

BRITISH JOURNAL OF UROLOGY, 1997, 80 (04) :597-605

[7]

Cambio Angelo J, 2007, Ther Clin Risk Manag, V3, P181

[8]

Chapple Christopher R, 2005, Rev Urol, V7 Suppl 4, pS22

[9] Efficacy and safety of silodosin in the treatment of lower urinary tract symptoms in elderly men taking antihypertensive medications [J].

Choi, Woo Suk ;

Cho, Min Chul ;

Lee, Jeong Woo ;

Song, Sang Hoon ;

Oh, Jin Kyu ;

Lee, Sang Wook ;

Cho, Sung Yong ;

Park, Jae Young .

PROSTATE INTERNATIONAL, 2017, 5 (03) :113-118

[10] Orthostatic hypotension in older people: considerations, diagnosis and management [J].

Dani, Melanie ;

Dirksen, Andreas ;

Taraborrelli, Patricia ;

Panagopolous, Dimitrios ;

Torocastro, Miriam ;

Sutton, Richard ;

Lim, Phang Boon .

CLINICAL MEDICINE, 2021, 21 (03) :E275-E282

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