Microbial Symphony: Navigating the Intricacies of the Human Oral Microbiome and Its Impact on Health

被引:8
作者
Bhandary, Rahul [1 ]
Venugopalan, Geethu [1 ]
Ramesh, Amitha [1 ]
Tartaglia, Guilia Margherita [2 ]
Singhal, Ishita [3 ]
Khijmatgar, Shahnawaz [4 ]
机构
[1] NITTE Deemed Univ, AB Shetty Mem Inst Dent Sci, Dept Periodontol, Mangalore 575018, India
[2] European Univ Madrid, Sch Med, Madrid 28670, Spain
[3] Univ Milan, Dept Biomed Surg & Dent Sci, I-20129 Milan, Italy
[4] Fdn IRCCS CaGranda Osped Maggiore Policlin, Milan, Italy
关键词
oral microbiome; microbial symphony; human health; microbial colonization; detection methodologies; disease progression; DNA-DNA HYBRIDIZATION; GENERATION SEQUENCING TECHNOLOGIES; MICROARRAY TECHNOLOGY; PERIODONTAL-DISEASE; MOLECULAR ANALYSIS; BACTERIAL; PCR; BIOFILMS; AMPLIFICATION; DIVERSITY;
D O I
10.3390/microorganisms12030571
中图分类号
Q93 [微生物学];
学科分类号
071005 ; 100705 ;
摘要
This comprehensive review delves into the forefront of research on the human oral microbiome, exploring recent advancements that span microbial colonization, state-of-the-art detection methodologies, and the complex interplay involved in disease progression. Through an exhaustive analysis of the contemporary literature, we illuminate the dynamic orchestration of microbial communities within the oral cavity, underscoring their pivotal role in health and disease. Cutting-edge detection techniques, including metagenomics and high-throughput sequencing, are discussed regarding their transformative impact on understanding the intricacies of oral microbial ecosystems. As we stand on the cusp of a new decade, this review anticipates a paradigm shift in the field, emphasizing the potential for rapid identification and targeted management of detrimental oral microorganisms. Insights gained from this exploration not only contribute to our fundamental understanding of the oral microbiome but also hold promise for the development of innovative therapeutic strategies to maintain oral health. This article aims to serve as a valuable resource for researchers, clinicians, and public health professionals engaged in unraveling the mysteries of the microbial symphony within the human oral cavity.
引用
收藏
页数:23
相关论文
共 146 条
[111]   Association between living environment and human oral viral ecology [J].
Robles-Sikisaka, Refugio ;
Ly, Melissa ;
Boehm, Tobias ;
Naidu, Mayuri ;
Salzman, Julia ;
Pride, David T. .
ISME JOURNAL, 2013, 7 (09) :1710-1724
[112]   DNA-DNA Hybridization [J].
Rossello-Mora, Ramon ;
Urdiain, Mercedes ;
Lopez-Lopez, Arantxa .
METHODS IN MICROBIOLOGY, VOL 38: TAXONOMY OF PROKARYOTES, 2011, 38 :325-347
[113]   Nature of symbiosis in oral disease [J].
Ruby, John ;
Goldner, Morris .
JOURNAL OF DENTAL RESEARCH, 2007, 86 (01) :8-11
[114]   A new era of long-read sequencing for cancer genomics [J].
Sakamoto, Yoshitaka ;
Sereewattanawoot, Sarun ;
Suzuki, Ayako .
JOURNAL OF HUMAN GENETICS, 2020, 65 (01) :3-10
[115]   Oral flora and pathogenic organisms [J].
Schuster, GS .
INFECTIOUS DISEASE CLINICS OF NORTH AMERICA, 1999, 13 (04) :757-+
[116]   Composition of the adult digestive tract bacterial microbiome based on seven mouth surfaces, tonsils, throat and stool samples [J].
Segata, Nicola ;
Haake, Susan Kinder ;
Mannon, Peter ;
Lemon, Katherine P. ;
Waldron, Levi ;
Gevers, Dirk ;
Huttenhower, Curtis ;
Izard, Jacques .
GENOME BIOLOGY, 2012, 13 (06) :R42
[117]   Are We Really Vastly Outnumbered? Revisiting the Ratio of Bacterial to Host Cells in Humans [J].
Sender, Ron ;
Fuchs, Shai ;
Milo, Ron .
CELL, 2016, 164 (03) :337-340
[118]  
Shaw LP, 2017, EMERG TOP LIFE SCI, V1, P287, DOI 10.1042/ETLS20170040
[119]   Microbial Geography of the Oral Cavity [J].
Simon-Soro, A. ;
Tomas, I. ;
Cabrera-Rubio, R. ;
Catalan, M. D. ;
Nyvad, B. ;
Mira, A. .
JOURNAL OF DENTAL RESEARCH, 2013, 92 (07) :616-621
[120]  
Singh J., 2014, Int. J. Adv. Res. Biol. Sci, V1, P65, DOI DOI 10.1007/S10529-013-1249-8