A voltammetric epinine sensor based on MWCNTs/ZnCo-ZIF nanocomposite and ionic liquid modified electrode

Epinine is prescribed as a natural medicine with the nature of catecholamine and pharmacologic properties similar to epinephrine. The current attempt was made to introduce a novel ultrasensitive epinine electrochemical sensor based on surface modification of carbon paste electrode (CPE) by using multi walled carbon nanotubes (MWCNTs)/Zn-Co zeolite imidazolate framework (ZnCo-ZIF) and n-hexyl-3-methylimidazolium hexafluorophosphate ionic liquid (IL) (MWCNTs/ZnCo-ZIF/IL/CPE sensor). The sensor possessed a commendable voltammetric response over the electro-oxidation of epinine with a linear dynamic range as broad as 0.08-375.0 mu M, a limit of detection (LOD) (S/N = 3) as narrow as 0.02 mu M, and a sensitivity as high as 0.1443 mu A/mM/cm2. The applicability of modified electrode was authenticated for sensing of epinine in the real specimens and as a result, appreciable relative standard deviations (RSDs) (1.9-3.5%) and recoveries (98.0-103.3%) were obtained.