Management of REM sleep behavior disorder: an American Academy of Sleep Medicine systematic review, meta-analysis, and GRADE assessment

被引：11

作者：

Howell, Michael ^{[1
,14
]}

Avidan, Alon Y. ^{[2
]}

Foldvary-Schaefer, Nancy ^{[3
]}

Malkani, Roneil G. ^{[4
,5
]}

During, Emmanuel H. ^{[6
,7
]}

Roland, Joshua P. ^{[8
,9
]}

McCarter, Stuart J. ^{[10
]}

Zak, Rochelle S. ^{[11
]}

Carandang, Gerard ^{[12
]}

Kazmi, Uzma ^{[12
]}

Ramar, Kannan ^{[13
]}

机构：

[1] Univ Minnesota, Dept Neurol, Minneapolis, MN USA

[2] UCLA, David Geffen Sch Med, Los Angeles, CA USA

[3] Cleveland Clin, Lerner Coll Med, Cleveland Hts, OH USA

[4] Northwestern Univ, Dept Neurol, Feinberg Sch Med, Chicago, IL USA

[5] Jesse Brown Vet Affairs Med Ctr, Chicago, IL USA

[6] Icahn Sch Med Mt Sinai, Dept Neurol, Div Movement Disorders, New York, NY USA

[7] Icahn Sch Med Mt Sinai, Dept Med, Div Pulm Crit Care & Sleep Med, New York, NY USA

[8] Thirty Madison, New York, NY USA

[9] UCLA, Dept Pulmonol Crit Care & Sleep Med, David Geffen Sch Med, Los Angeles, CA USA

[10] Mayo Clin, Dept Neurol, Coll Med, Rochester, MN USA

[11] Univ Calif San Francisco, Sleep Disorders Ctr, San Francisco, CA USA

[12] Amer Acad Sleep Med, Darien, IL USA

[13] Mayo Clin, Ctr Sleep Med, Div Pulm & Crit Care Med, Rochester, MN USA

[14] Univ Minnesota, Dept Neurol, 516 Delaware St SE, Minneapolis, MN 55455 USA

来源：

JOURNAL OF CLINICAL SLEEP MEDICINE | 2023年 / 19卷 / 04期

关键词：

REM sleep; REM sleep behavior disorder; parasomnia; dream enactment; sleep disorder; narcolepsy; Parkinson's disease; dementia with Lewy bodies; EYE-MOVEMENT SLEEP; RESTLESS LEGS SYNDROME; PARKINSONS-DISEASE; LEWY BODIES; TREATMENT OUTCOMES; DRUG-TREATMENT; DOUBLE-BLIND; OPEN-LABEL; LONG-TERM; PATIENT;

D O I：

10.5664/jcsm.10426

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

This systematic review provides supporting evidence for a clinical practice guideline for the management of rapid eye movement (REM) sleep behavior disorder in adults and children. The American Academy of Sleep Medicine commissioned a task force of 7 experts in sleep medicine. A systematic review was conducted to identify randomized controlled trials and observational studies that addressed interventions for the management of REM sleep behavior disorder in adults and children. Statistical analyses were performed to determine the clinical significance of critical and important outcomes. Finally, the Grading of Recommendations, Assessment, Development, and Evaluation (GRADE) process was used to assess the evidence for making recommendations. The literature search identified 4,690 studies; 148 studies provided data suitable for statistical analyses; evidence for 45 interventions is presented. The task force provided a detailed summary of the evidence assessing the certainty of evidence, the balance of benefits and harms, patient values and preferences, and resource use considerations.

引用

页码：769 / 810

页数：42

共 166 条

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