Amino-SBBF (Single Benzene-based Fluorophore) Library: Its Synthesis, Photophysical Property, and Cellular Imaging Application

被引：15

作者：

Jin, Ji Hye ^{[1
]}

An, Jong Min ^{[1
]}

Kim, Dopil ^{[2
]}

Lee, Sangho ^{[2
]}

Kim, Min ^{[2
,11
]}

Kim, Dokyoung ^{[1
,3
,4
,5
,6
,7
,8
,9
,10
]}

机构：

[1] Kyung Hee Univ, Grad Sch, Dept Biomed Sci & Technol, Seoul 02447, South Korea

[2] Chungbuk Natl Univ, Dept Chem, Cheongju 28644, South Korea

[3] Kyung Hee Univ, Coll Med, Dept Anat & Neurobiol, Seoul 02447, South Korea

[4] Kyung Hee Univ, Med Res Ctr Bioreact React Oxygen Species, Seoul 02447, South Korea

[5] Kyung Hee Univ, Biomed Sci Inst, Core Res Inst CRI, Seoul 02447, South Korea

[6] Kyung Hee Univ, Ctr Converging Humanities, Seoul 02447, South Korea

[7] Kyung Hee Univ, KHU KIST Dept Converging Sci & Technol, Seoul 02447, South Korea

[8] Kyung Hee Univ, Coll Med, Dept Precis Med, Seoul 02447, South Korea

[9] UC San Diego Mat Res Sci & Engn Ctr, 9500 Gilman Dr, La Jolla, CA 92093 USA

[10] Kyung Hee Univ Hosp, Seoul, South Korea

[11] Chungbuk Natl Univ, Cheongju, South Korea

来源：

DYES AND PIGMENTS | 2024年 / 221卷

基金：

新加坡国家研究基金会;

关键词：

Single benzene-based fluorophore (SBBFs); Solvatochromism; Two-photon emission; Bio-imaging; FLUORESCENCE; EMISSION; PROBES;

D O I：

10.1016/j.dyepig.2023.111811

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

Single benzene-based fluorophore (SBBF) is a representative small-size fluorescent dye which has an electron push-pull structure within a benzene backbone. In this work, we disclosed a new amino-SBBF (ASBBF) library that has various alkyl-amines and aromatic-amines on the electron-donating site. The synthesis, photophysical properties, quantum chemical calculation, two-photon responsiveness, and bioimaging applicability of ASBBF in cells were successfully identified. We believe that our present work provides a guide to the development of new fluorescent materials and molecular probes in various research fields.

引用

页数：8

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