LANIFIBRANOR IMPROVES LIVER HISTOLOGY AND MARKERS OF CARDIOMETABOLIC HEALTH IN PATIENTS WITH NASH INDEPENDENT OF PNPLA3 GENOTYPE: A RETROSPECTIVE ANALYSIS OF THE NATIVE STUDY

被引：0
|
作者：
Griffel, Louis H. [1 ]
Francque, Sven [2 ]
Abdelmalek, Manal F. [3 ]
Huot-Marchand, Philippe [1 ]
Baudin, Lucile Dzen Martine [1 ]
Junien, Jean Louis [1 ]
Broqua, Pierre [1 ]
Cooreman, Michael [1 ]
机构：
[1] Inventiva, Daix, France
[2] Univ Antwerp, Edegem, Belgium
[3] Mayo Clin, Rochester, MN USA
来源：
HEPATOLOGY | 2023年 / 78卷
关键词：
D O I：
暂无
中图分类号：
R57 [消化系及腹部疾病];
学科分类号：
摘要：
2457-C
引用
收藏
页码：S1202 / S1203
页数：2
相关论文
共 17 条
  • [1] The pan-PPAR agonist lanifibranor improves markers of cardiometabolic health in patients with NASH independent of weight change
    Cooreman, Michael
    Francque, Sven
    Baudin, Martine
    Huot-Marchand, Philippe
    Dzen, Lucile
    Junien, Jean-Louis
    Broqua, Pierre
    Abdelmalek, Manal
    JOURNAL OF HEPATOLOGY, 2022, 77 : S721 - S722
  • [2] Lanifibranor Improves Markers of Cardiometabolic Health in Patients with NASH and Type 2 Diabetes, Correlated with Responses in Adiponectin Levels
    Griffel, Louis H.
    Francque, Sven
    Abdelmalek, Manal F.
    Huot-Marchand, Philippe
    Dzen, Lucile
    Baudin, Martine
    Junien, Jean L.
    Broqua, Pierre
    Cooreman, Michael P.
    DIABETES, 2023, 72
  • [3] RS738409GG GENOTYPE OF PNPLA3 IN PATIENTS WITH MEDICALLY COMPLICATED OBESITY - CORRELATIONS WITH LIVER HISTOLOGY (NASH), INSULIN RESISTANCE AND FIBRINOGEN
    Guichelaar, Maureen
    Gawrieh, Samer
    Viker, Kimberly
    Krishnan, Anuradha
    Charlton, Michael R.
    HEPATOLOGY, 2010, 52 (04) : 450A - 451A
  • [4] Among Nonalcoholic Fatty Liver Disease Patients Treated With Phlebotomy Does PNPLA3 Genotype Influence Changes in Gene Expression, Adipokines and Liver Histology?
    Beaton, Melanie D.
    Summers, Kelly
    Woolsey, Sarah
    Choi, Yun-Hee
    Tirona, Rommel G.
    GASTROENTEROLOGY, 2013, 144 (05) : S1010 - S1010
  • [5] Lanifibranor therapy improves markers of lipid metabolism, insulin resistance, liver injury and fibrosis in patients with NASH and F2 and F3 fibrosis stages: a subgroup analysis of the phase 2b NATIVE study
    Francque, Sven
    Cooreman, Michael
    Baudin, Martine
    Huot-Marchand, Philippe
    Dzen, Lucile
    Louis, Junien Jean
    Broqua, Pierre
    Abdelmalek, Manal
    JOURNAL OF HEPATOLOGY, 2021, 75 : S268 - S269
  • [6] Early aminotransferase improvement in the phase 2b NATIVE study is predictive of response pattern of liver histology as well as hepatic and cardiometabolic health markers at the end of treatment in patients with non-cirrhotic NASH
    Anstee, Quentin
    Huot-Marchand, Philippe
    Dzen, Lucile
    Junien, Jean-Louis
    Broqua, Pierre
    Francque, Sven
    Abdelmalek, Manal
    Cooreman, Michael
    Harrison, Stephen
    JOURNAL OF HEPATOLOGY, 2023, 78 : S651 - S651
  • [7] Abdominal Fat and Metabolic Health Markers but Not PNPLA3 Genotype Predicts Liver Fat Accumulation in Response to Excess Intake of Energy and Saturated Fat in Healthy Individuals
    Rosqvist, Fredrik
    Orho-Melander, Marju
    Kullberg, Joel
    Iggman, David
    Johansson, Hans-Erik
    Cedernaes, Jonathan
    Ahlstrom, Hakan
    Riserus, Ulf
    FRONTIERS IN NUTRITION, 2020, 7
  • [8] A prospective Study for Evaluating the Ffficacy of a standardized, low-calorie Diet (HEPAFAST-Shake) as a Function of the PNPLA3 Genotype in Patients with a Fatty Liver Disease
    Teufelhart, Manuela
    Hofer, Harald
    Haslacher, Helmuth
    Meyer, Bernhard
    Winker, Robert
    Ferenci, Peter
    Mehl, Benedikt
    Rabitsch, Christian
    Nistler, Sonja
    Trauner, Michael
    Scherzer, Thomas-Matthias
    WIENER KLINISCHE WOCHENSCHRIFT, 2016, 128 (19-20) : 740 - 740
  • [9] A prospective study to evaluate the efficacy of a standardized low calorie diet according to PNPLA3 genotype in patients with Non Alcoholic Fatty Liver Disease (NAFLD) - week 2 data interim analysis
    Teufelhart, Manuela
    Hofer, Harald
    Haslacher, Helmuth
    Winker, Robert
    Meyer, Bernhard
    Ferenci, Peter
    Mehl, Benedikt
    Rabitsch, Christian
    Nistler, Sonja
    Trauner, Michael H.
    Scherzer, Thomas-Matthias
    HEPATOLOGY, 2016, 64 : 588A - 588A
  • [10] A prospective study to evaluate the efficacy of a standardized low calorie diet according to PNPLA3 genotype in patients with Non Alcoholic Fatty Liver Disease (NAFLD)-2 months data (interim analysis)
    Teufelhart, M.
    Hofer, H.
    Haslacher, H.
    Winker, R.
    Meyer, B.
    Ferenci, P.
    Mehl, B.
    Rabitsch, C.
    Nistler, S.
    Trauner, M.
    Scherzer, T. -M
    JOURNAL OF HEPATOLOGY, 2017, 66 (01) : S422 - S422
12