Functionalized amino Al-MOF as a novel fluorescence chemosensor for determination of Pb2+ in aqueous solution

Lead is an environmental pollutant that has been present for a long time and has harmful effects on human health. The essential task of protecting public health requires sensitivity and selectivity in monitoring and removing Pb2+ from the environment. NH2-Al-MOF was utilized to create a chemical sensor that can quickly detect Pb2+ ions. By combining the Al-metal-organic framework (MOF) with 2-Acetyl-4-methylpyridine, the 2A4MP=N-Al-MOF sensor was developed. The NH2-Al-MOF and 2A4MP=N-Al-MOF sensor were characterized by X-ray photoelectron spectroscopy (XPS), Brunner-Emmet-Teller (BET), X-ray diffractometer (XRD), Fourier transform infrared (FT-IR), and scanning electron microscopy (SEM). Characterization results indicate that 2-Acetyl-4-methylpyridine was effectively incorporated into the Al-based MOF, and the 2A4MP=N-Al-MOF sensor's pore structure is primarily made up of mesopores. To determine the optimal conditions for detecting Pb2+ ions using the 2A4MP=N-Al-MOF sensor via fluorescence measurement, several experimental studies have been carried out. A steady spectroscopic signal can be achieved with a sensor that has a response time of below 30 seconds. According to ICH guidelines, the suggested methods underwent validation for LOD, LOQ, linearity, and precision. The results show that the 2A4MP=N-Al-MOF chemosensor has a high sensitivity and selectivity toward the Pb2+ analyte, with a detection limit of 0.171 ppm and a linear range of 0.0-2.0 ppm. The 2A4MP=N-Al-MOF chemosensor also exhibited good reproducibility, with a relative standard deviation of less than 3%. As a result, the Pb2+ ions were sensitively and selectively identified in various environmental water samples using the 2A4MP=N-Al-MOF sensor.