Boryl Radical-Promoted Deoxygenative Alkylation of Benzyl Acetates

被引：0
作者：
Liu, Nan-Nan [1 ]
Wan, Xuan-Chen [1 ]
Hui, Li-Wen [1 ]
Zhang, Feng-Lian [1 ]
Wang, Yi-Feng [1 ]
机构：
[1] Univ Sci & Technol China, Dept Chem, 96 Jinzhai Rd, Hefei 230026, Anhui, Peoples R China
来源：
SYNTHESIS-STUTTGART | 2024年 / 56卷 / 11期
基金：
中国国家自然科学基金;
关键词：
deoxygenative alkylation; C-O bond activation; reduction; boryl radical; CARBOXYLIC-ACIDS; ALCOHOLS; PHOTOREDOX; CATALYSIS; OXALATES; ACTIVATION; GENERATION; REDUCTION; COMPLEXES; MECHANISM;
D O I：
10.1055/s-0042-1751463
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
Deoxygenative alkylation of benzyl alcohols was realized by using acetate as the alcohol activation group. The C-O bond homolysis is achieved by a boryl radical-promoted beta-scission process. The strategy is amenable to a variety of benzyl alcohols, including primary, secondary, and more challenging tertiary alcohols. The synthetic practicability was demonstrated by a gram-scale one-pot reaction.
引用
收藏
页码：1719 / 1726
页数：8
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