Autologous hematopoietic stem cell transplantation in a patient with refractory Crohn's disease

被引：0

作者：

Ortega, Ana Gordo ^{[1
]}

Ubegun, Maren Eizaguirre ^{[1
]}

Trebol, Martin Balerdi ^{[1
]}

Iturria, Saioa Rubio ^{[1
]}

Gutierrez, Cristina Rodriguez ^{[1
]}

机构：

[1] Hosp Univ Navarra, Serv Navarro Salud Osasunbidea, Serv Aparato Digest, Pamplona, Spain

来源：

ANALES DEL SISTEMA SANITARIO DE NAVARRA | 2023年 / 46卷 / 03期

关键词：

Crohn disease; Transplantation; autologous; Hematopoietic stem cell; Bone marrow;

D O I：

10.23938/ASSN.1054

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Crohn's disease is a chronic condition for which some-times there is no effective medical or surgical treatment. Autologous hematopoietic stem cell transplantation may be a therapeutic option for these patients to restore immune tolerance. Consequently, this may lead to remission of the disease or decrease its activity, making drugs that have previously failed be effective. Due to the safety profile of the procedure and the fact that it is a non-curative treatment, patient selection must be rigorous.We report our experience with the first patient selected in our centre for autologous hematopoietic stem cell transplantation: 27 years old male with Crohn's dis-ease (A1L3B1p) refractory to multiple lines of medical treatment and not a candidate for surgical treatment. Two years after the transplantation, the patient remains asymptomatic.

引用

页数：3

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