Recent Advances in Polymer-Based Nanomaterials for Non-Invasive Photothermal Therapy of Arthritis

被引：13

作者：

Tekade, Muktika ^{[1
]}

Pingale, Prashant ^{[2
]}

Gupta, Rachna ^{[3
]}

Pawar, Bhakti ^{[3
]}

Tekade, Rakesh Kumar ^{[3
]}

Sharma, Mukesh Chandra ^{[1
]}

机构：

[1] Devi Ahilya Vishwavidyalaya, Sch Pharm, Takshila Campus,Khandwa Rd, Indore 452001, Madhya Pradesh, India

[2] Sir Dr MS Gosavi Coll Pharmaceut Educ & Res, Dept Pharmaceut, Nasik 422005, Maharashtra, India

[3] Natl Inst Pharmaceut Educ & Res NIPER, Opp AF Stn, Ahmadabad 382355, Gujarat, India

来源：

PHARMACEUTICS | 2023年 / 15卷 / 03期

关键词：

polymer; nanomaterials; photothermal; arthritis; near infra-red; inflammation; drugs; RHEUMATOID-ARTHRITIS; PHOTODYNAMIC THERAPY; T-CELLS; NANOPARTICLES; SIRNA; PHOTOSENSITIZERS; DEXAMETHASONE; MECHANISMS; DELIVERY;

D O I：

10.3390/pharmaceutics15030735

中图分类号：

R9 [药学];

学科分类号：

1007 ;

摘要：

To date, nanomaterials have been widely used for the treatment and diagnosis of rheumatoid arthritis. Amongst various nanomaterials, polymer-based nanomaterials are becoming increasingly popular in nanomedicine due to their functionalised fabrication and easy synthesis, making them biocompatible, cost-effective, biodegradable, and efficient nanocarriers for the delivery of drugs to a specific target cell. They act as photothermal reagents with high absorption in the near-infrared region that can transform near-infrared light into localised heat with fewer side effects, provide easier integration with existing therapies, and offer increased effectiveness. They have been combined with photothermal therapy to understand the chemical and physical activities behind the stimuli-responsiveness of polymer nanomaterials. In this review article, we provide detailed information regarding the recent advances in polymer nanomaterials for the non-invasive photothermal treatment of arthritis. The synergistic effect of polymer nanomaterials and photothermal therapy has enhanced the treatment and diagnosis of arthritis and reduced the side effects of drugs in the joint cavity. In addition, further novel challenges and future perspectives must be resolved to advance polymer nanomaterials for the photothermal therapy of arthritis.

引用

页数：24

共 49 条

[1] T-cell contact-dependent regulation of CC and CXC chemokine production in monocytes through differential involvement of NFκB:: implications for rheumatoid arthritis [J].

Beech, Jonathan T. ;

Andreakos, Evangelos ;

Ciesielski, Cathleen J. ;

Green, Patricia ;

Foxwell, Brian M. J. ;

Brennan, Fionula M. .

ARTHRITIS RESEARCH & THERAPY, 2006, 8 (06)

[2] Mechanisms in photodynamic therapy: part one-photosensitizers, photochemistry and cellular localization [J].

Castano, Ana P. ;

Demidova, Tatiana N. ;

Hamblin, Michael R. .

PHOTODIAGNOSIS AND PHOTODYNAMIC THERAPY, 2004, 1 (04) :279-293

[3] Recent approaches for targeted drug delivery in rheumatoid arthritis diagnosis and treatment [J].

Chegini, Sana Pirmardvand ;

Varshosaz, Jaleh ;

Taymouri, Somayeh .

ARTIFICIAL CELLS NANOMEDICINE AND BIOTECHNOLOGY, 2018, 46 :502-514

[4] Targeted Superparamagnetic Iron Oxide Nanoparticles for In Vivo Magnetic Resonance Imaging of T-Cells in Rheumatoid Arthritis [J].

Chen, Chih-Lung ;

Siow, Tiing Yee ;

Chou, Cheng-Hung ;

Lin, Chen-Hsuan ;

Lin, Ming-Huang ;

Chen, Yung-Chu ;

Hsieh, Wen-Yuan ;

Wang, Shian-Jy ;

Chang, Chen .

MOLECULAR IMAGING AND BIOLOGY, 2017, 19 (02) :233-244

[5] A core-shell structure QRu-PLGA-RES-DS NP nanocomposite with photothermal response-induced M2 macrophage polarization for rheumatoid arthritis therapy [J].

Chen, Xu ;

Zhu, Xufeng ;

Ma, Litao ;

Lin, Ange ;

Gong, Youcong ;

Yuan, Guanglong ;

Liu, Jie .

NANOSCALE, 2019, 11 (39) :18209-18223

[6] A photothermal-triggered nitric oxide nanogenerator combined with siRNA for precise therapy of osteoarthritis by suppressing macrophage inftammation [J].

Chen, Xu ;

Liu, Yanan ;

Wen, Yayu ;

Yu, Qianqian ;

Liu, Jiawei ;

Zhao, Yingyu ;

Liu, Jie ;

Ye, Gang .

NANOSCALE, 2019, 11 (14) :6693-6709

[7] Targeted hexagonal Pd nanosheet combination therapy for rheumatoid arthritis via the photothermal controlled release of MTX [J].

Chen, Xu ;

Zhu, Xufeng ;

Xu, Taoyuan ;

Xu, Mengmeng ;

Wen, Yayu ;

Liu, Yanan ;

Liu, Jie ;

Qin, Xiuying .

JOURNAL OF MATERIALS CHEMISTRY B, 2019, 7 (01) :112-122

[8] Topical delivery of anti-TNFα siRNA and capsaicin via novel lipid-polymer hybrid nanoparticles efficiently inhibits skin inflammation in vivo [J].

Desai, Pinaki R. ;

Marepally, Srujan ;

Patel, Apurva R. ;

Voshavar, Chandrashekhar ;

Chaudhuri, Arabinda ;

Singh, Mandip .

JOURNAL OF CONTROLLED RELEASE, 2013, 170 (01) :51-63

[9] Utilization of nanoparticle technology in rheumatoid arthritis treatment [J].

Dolati, Sanam ;

Sadreddini, Sanam ;

Rostamzadeh, Davoud ;

Ahmadi, Majid ;

Jadidi-Niaragh, Farhad ;

Yousefi, Mehdi .

BIOMEDICINE & PHARMACOTHERAPY, 2016, 80 :30-41

[10] Nanotechnology-Based Drug Delivery Systems for Photodynamic Therapy of Cancer: A Review [J].

Fioramonti Calixto, Giovana Maria ;

Bernegossi, Jessica ;

de Freitas, Laura Marise ;

Fontana, Carla Raquel ;

Chorilli, Marlus .

MOLECULES, 2016, 21 (03)

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