Advanced Taste-Masking Methods of Solid Dosage Forms

被引：1
作者：
Bueva, V. V. [1 ]
Blynskaja, E. V. [1 ]
Alekseev, K. V. [1 ]
Minaev, S. V. [1 ]
Eremin, V. A. [2 ]
机构：
[1] Res Zakusov Inst Pharmacol, 8 Baltiiskaya St, Moscow 125315, Russia
[2] Peoples Friendship Univ Russia, Inst Biochem Technol & Nanotechnol, 10 Miklukho Maklaya St, Moscow 117198, Russia
来源：
PHARMACEUTICAL CHEMISTRY JOURNAL | 2023年 / 57卷 / 09期
关键词：
taste masking; multidose systems; sweeteners; film coatings; flavorings; PARTICULATE SYSTEMS; RELEASE; MICROPARTICLES; ENCAPSULATION; TABLETS; RESIN;
D O I：
10.1007/s11094-023-03015-8
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
One of the main problems in medical practice is the lack of patient adherence to treatment, which is often attributed to the bitterness or sourness of medicines causing discomfort and an aversion during administration, especially in children. Therefore, masking an unpleasant taste is one of the goals of pharmaceutical development. Currently, there are various approaches to improving the taste of oral dosage forms containing bitter or excessively sour pharmaceutical substances. This review covers some of these approaches and their advantages and disadvantages and provides relevant examples of the possible use of each of them.
引用
收藏
页码：1494 / 1498
页数：5
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