Comparative analysis of early post-operative outcomes between retzius-sparing and anterior approach robotic radical prostatectomy for a single surgeon

被引:3
作者
Tay, Li June [1 ]
Makin, Robert [1 ]
Saxionis, Ioannis [1 ]
Dokubo, Ibi [1 ]
Patel, Keval [2 ]
Sivathasan, Sailantra [3 ]
Smart, Sonny [4 ]
Warren, Anne [5 ]
Shah, Nimish [1 ]
Lamb, Benjamin W. [4 ,6 ,7 ]
机构
[1] Cambridge Univ Hosp, Dept Urol, Cambridge, England
[2] Univ Hosp Birmingham, Dept Urol, Birmingham, England
[3] Western Gen Hosp, Dept Urol, Edinburgh, Scotland
[4] Univ Coll London Hosp NHS Trust, Dept Urol, London, England
[5] Cambridge Univ Hosp, Dept Pathol, Cambridge, England
[6] Anglia Ruskin Univ, Fac Hlth Educ Med & Social Care, Cambridge, England
[7] Barts Hlth NHS Trust, Dept Urol, London, England
关键词
Retzius-sparing; learning curve; training; robot-assisted radical prostatectomy; oncological control; functional outcomes;
D O I
10.1177/20514158231156314
中图分类号
R5 [内科学]; R69 [泌尿科学(泌尿生殖系疾病)];
学科分类号
1002 ; 100201 ;
摘要
Introduction: The aim of this study was to compare intraoperative and early post-operative outcomes between retzius-sparing robotic-assisted radical prostatectomy (RS-RARP) versus standard approach for RARP (S-RARP). Patients and methods: All RARPs by a single surgeon were included and divided into two groups: (1) standard approach including combined anterior-posterior approach (S-RARP); (2) retzius-sparing posterior approach (RS-RARP). Allocation was based on prostate size and location of index lesion on MRI. Initial post-operative follow-up was at 6 weeks. Results: Overall, 169 RARPs were performed between March 2018 and October 2021: S-RARP = 99 versus RS-RARP = 70. There was no significant difference in pre-operative body mass index (BMI), prostate-specific antigen (PSA), International Society of Urological Pathology (ISUP) grade group and clinical T stage. Intraoperative differences were found in blood loss (300 versus 200 mL, p = 0.008), console time (180 versus 135 minutes, p < 0.001) favouring RS-RARP, with no differences in nerve-spare or lymph node dissection. Post-operatively, no difference was found in ISUP grade, pathological T stage, positive surgical margins, number of lymph nodes sampled, readmissions or complications. Gland size in the RS group was smaller (38 versus 29 g, p = 0.001). Early (6 weeks) post-op follow-up showed a significant difference between groups for both pad-free continence (35% versus 53%, p = 0.011) and social continence (79% versus 89%, p = 0.024), but no difference for erectile function recovery (27% versus 50% of baseline) and post-op PSA levels < 0.1 ng/mL (85% versus 93%). Conclusion: Even early in the learning curve, continence recovery, operative time and blood loss were significantly better for RS-RARP than S-RARP. Margin status and PSA levels are comparable to published literature for both groups. Standardised training in RS-RARP might help to improve the uptake of this novel technique.
引用
收藏
页码:114 / 120
页数:7
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