Developmental predictors of young adult borderline personality disorder: a prospective, longitudinal study of females with and without childhood ADHD

被引:4
作者
O'Grady, Sinclaire M. M. [1 ]
Hinshaw, Stephen P. P. [1 ,2 ]
机构
[1] Univ Calif Berkeley, Dept Psychol, 2121 Berkeley Way West, Berkeley, CA 94720 USA
[2] Univ Calif San Francisco, Dept Psychiat & Behav Sci, 675 18th St, San Francisco, CA 94107 USA
关键词
Borderline personality disorder; Attention-deficit hyperactivity disorder; Risk factors; Longitudinal studies; Adverse childhood experiences; ATTENTION-DEFICIT/HYPERACTIVITY DISORDER; DEFICIT HYPERACTIVITY DISORDER; RANDOMIZED CLINICAL-TRIAL; PROSPECTIVE FOLLOW-UP; DIALECTICAL BEHAVIOR-THERAPY; OSTERRIETH COMPLEX FIGURE; PSYCHIATRIC-DISORDERS; RETROSPECTIVE REPORTS; PREADOLESCENT GIRLS; EXECUTIVE FUNCTIONS;
D O I
10.1186/s12888-023-04515-3
中图分类号
R749 [精神病学];
学科分类号
100205 ;
摘要
BackgroundResearch on the precursors of borderline personality disorder (BPD) reveals numerous child and adolescent risk factors, with impulsivity and trauma among the most salient. Yet few prospective longitudinal studies have examined pathways to BPD, particularly with inclusion of multiple risk domains.MethodsWe examined theory-informed predictors of young-adult BPD (a) diagnosis and (b) dimensional features from childhood and late adolescence via a diverse (47% non-white) sample of females with (n = 140) and without (n = 88) carefully diagnosed childhood attention-deficit hyperactivity disorder (ADHD).ResultsAfter adjustment for key covariates, low levels of objectively measured executive functioning in childhood predicted young adult BPD diagnostic status, as did a cumulative history of childhood adverse experiences/trauma. Additionally, both childhood hyperactivity/impulsivity and childhood adverse experiences/trauma predicted young adult BPD dimensional features. Regarding late-adolescent predictors, no significant predictors emerged regarding BPD diagnosis, but internalizing and externalizing symptoms were each significant predictors of BPD dimensional features. Exploratory moderator analyses revealed that predictions to BPD dimensional features from low executive functioning were heightened in the presence of low socioeconomic status.ConclusionsGiven our sample size, caution is needed when drawing implications. Possible future directions include focus on preventive interventions in populations with enhanced risk for BPD, particularly those focused on improving executive functioning skills and reducing risk for trauma (and its manifestations). Replication is required, as are sensitive measures of early emotional invalidation and extensions to male samples.
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页数:17
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