Two new sesquiterpenes from Xylopia vielana

被引：0
作者：
Chen, Ling [1 ]
Yang, Ping [1 ]
Zhang, Mi [1 ]
Dai, Weifeng [1 ]
机构：
[1] Kunming Univ Sci & Technol, Fac Life Sci & Technol, Kunming 650500, Yunnan, Peoples R China
来源：
NATURAL PRODUCT RESEARCH | 2023年 / 37卷 / 07期
基金：
中国国家自然科学基金;
关键词：
Xylopia vielana; sesquiterpenes; NO inhibitory effects;
D O I：
10.1080/14786419.2021.1984907
中图分类号：
O69 [应用化学];
学科分类号：
081704 ;
摘要：
Two new sesquiterpenes (1-2) and six known analogues (3-8) were isolated from the branches and leaves of Xylopia vielana Pierre. The structures of the new compounds were identified by analyzing 1 D and 2 D NMR data and HRESIMS data, combined with induced and calculated circular dichroism experiments. In addition, compounds 1-4, 7 and 8 showed notable nitric oxide (NO) inhibitory effects (IC50 < 10 mu M) on the model of the lipopolysaccharide (LPS)-activated RAW 264.7 macrophages.
引用
收藏
页码：1199 / 1204
页数：6
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