Solubility and Thermodynamic Modeling of 5-Nitrofurazone in Pure Solvents and Binary Solvent Mixtures

被引：8

作者：

Li, Jun ^{[1
]}

Yan, Xiaoyang ^{[1
]}

Li, Xin ^{[1
]}

Chen, Wei ^{[1
,2
]}

Wang, Ting ^{[1
,2
]}

Hao, Hongxun ^{[1
,2
]}

Wang, Na ^{[1
,2
]}

Huang, Xin ^{[1
,2
]}

机构：

[1] Tianjin Univ, Natl Engn Res Ctr Ind Crystallizat Technol, Sch Chem Engn & Technol, Tianjin 300072, Peoples R China

[2] Collaborat Innovat Ctr Chem Sci & Engn Tianjin, Tianjin 300072, Peoples R China

来源：

JOURNAL OF CHEMICAL AND ENGINEERING DATA | 2023年 / 68卷 / 06期

基金：

中国国家自然科学基金;

关键词：

MELTING-POINTS; TEMPERATURES; WATER; ACID;

D O I：

10.1021/acs.jced.3c00112

中图分类号：

O414.1 [热力学];

学科分类号：

摘要：

In this work, the solubility of 5-nitrofurazone (Form alpha) in 10 pure solvents (water, methanol, ethanol, acetonitrile,ethyl acetate, n-propanol, isopropanol, acetone,formamide, N,N-dimethylformamide)and two binary mixed solvents (N,N-dimethylformamide + water, N,N-dimethylformamide + acetonitrile) were measured by ultraviolet-visiblespectrophotometry from 278.15 to 313.15 K. The experimental resultsshowed that the solubility of 5-nitrofurazone (Form alpha) in allpure solvents and binary mixed solvents was positively correlatedwith temperature. Additionally, the modified Apelblat equation, the lambda h equation, and the nonrandom two-liquid (NRTL)model were used to correlate the experimental solubility results.The results showed that all of these models could correlate the experimentaldata well, and the modified Apelblat equation provided the best fittingresults. Finally, the mixing and dissolution thermodynamic propertiesof 5-nitrofurazone (Form alpha) in 10 pure solvents and two binarysolvents, including enthalpy, entropy, and Gibbs energy, were calculatedby experimental results and the NRTL model.

引用

页码：1460 / 1475

页数：16

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