Alcohol and breast cancer

被引:30
作者
Starek-Swiechowicz, Beata [1 ]
Budziszewska, Boguslawa [1 ]
Starek, Andrzej [1 ]
机构
[1] Jagiellonian Univ, Med Coll, Chair Toxicol, Dept Biochem Toxicol, Med 9, PL-30688 Krakow, Poland
关键词
Ethanol metabolism; Breast cancer; Breast cancer risk factors; Alcohol and oestrogens; Preventive factors; PROGESTERONE-RECEPTOR STATUS; OXIDASE INHIBITORY-ACTIVITY; ALDEHYDE DEHYDROGENASE; POSTMENOPAUSAL WOMEN; POOLED ANALYSIS; ER-ALPHA; ETHANOL; RISK; CONSUMPTION; ESTROGEN;
D O I
10.1007/s43440-022-00426-4
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Breast cancer is one of the main causes of death in women worldwide. In women, breast cancer includes over half of all tumours caused by alcohol. This paper discusses both ethanol metabolism and the mechanisms of mammary tumourigenesis caused by alcohol. Numerous signalling pathways in neoplastic transformation following alcohol consumption in women have been presented. In addition, primary and secondary prevention, phytochemicals, synthetic chemicals, specific inhibitors of enzymes and selective receptor modulators have been described.
引用
收藏
页码:69 / 84
页数:16
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