The Use of Brain Natriuretic Peptide in the Evaluation of Heart Failure in Geriatric Patients

被引：13

作者：

Marinescu, Mihai ^{[1
,2
]}

Oprea, Violeta Diana ^{[1
,2
]}

Nechita, Aurel ^{[1
,3
]}

Tutunaru, Dana ^{[1
,2
]}

Nechita, Luiza-Camelia ^{[1
,2
]}

Romila, Aurelia ^{[1
,2
]}

机构：

[1] Dunarea de Jos Univ Galati, Fac Med & Pharm, Galati 800216, Romania

[2] St Apostle Andrei Clin Emergency Cty Hosp, Galati 800578, Romania

[3] St Ioan Emergency Clin Hosp Children, Galati 800487, Romania

来源：

DIAGNOSTICS | 2023年 / 13卷 / 09期

关键词：

heart failure in geriatric population; natriuretic peptides in heart failure; BNP; NTproBNP; ELDERLY-PATIENTS; EMERGENCY DIAGNOSIS; CLINICAL-RELEVANCE; EJECTION FRACTION; MEDICAL THERAPY; OLDER PATIENTS; AGE; DETERMINANTS; MANAGEMENT; MORTALITY;

D O I：

10.3390/diagnostics13091512

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

Heart failure is one of the main morbidity and mortality factors in the general population and especially in elderly patients. Thus, at the European level, the prevalence of heart failure is 1% in people under 55 years of age but increases to over 10% in people over 70 years of age. The particularities of the elderly patient, which make the management of heart failure difficult, are the presence of comorbidities, frailty, cognitive impairment and polypharmacy. However, elderly patients are under-represented in clinical trials on the diagnosis and treatment of heart failure. The need for complementary methods (biomarkers) for differential and early diagnosis of heart failure is becoming more and more evident, even in its subclinical stages. These methods need to have increased specificity and sensitivity and be widely available. Natriuretic peptides, in particular B-type natriuretic peptide (BNP) and its fraction NTproBNP, have gained an increasingly important role in the screening, diagnosis and treatment of heart failure in recent years.

引用

页数：12

共 58 条

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