Current Practice Review in the Management of Acute Respiratory Distress Syndrome

被引:1
作者
Chudow, Melissa B. [1 ]
Condeni, Melanie S. [2 ]
Dhar, Sanjay [3 ]
Heavner, Mojdeh S. [4 ]
Nei, Andrea M. [5 ]
Bissell, Brittany D. [6 ]
机构
[1] Univ S Florida, Taneja Coll Pharm, Dept Pharmacotherapeut & Clin Res, Tampa, FL 33620 USA
[2] Med Univ South Carolina, MUSC Coll Pharm, Charleston, SC 29425 USA
[3] Univ Kentucky, Pulmonary Crit Care Ultrasound & Res, Pulm & Crit Care Fellowship Program, Div Pulm Crit Care & Sleep Med, Lexington, KY USA
[4] Univ Maryland, Sch Pharm, Dept Pharm Practice & Sci, Baltimore, MD 21201 USA
[5] Mayo Clin Hosp, Dept Pharm, Mayo Clin Coll Med Sci, Crit Care Pharmacist, Rochester, MN USA
[6] Univ Kentucky, Coll Pharm, Dept Pharm Practice & Sci, 800 Rose St,H110, Lexington, KY 40536 USA
关键词
acute respiratory distress syndrome; corticosteroids; neuromuscular-blocking agents; critical care; EXTRACORPOREAL MEMBRANE-OXYGENATION; ACUTE LUNG INJURY; NEUROMUSCULAR BLOCKING-AGENTS; SURVIVING SEPSIS CAMPAIGN; CLINICAL-PRACTICE GUIDELINES; CRITICALLY-ILL PATIENTS; SEPTIC SHOCK; TIDAL VOLUME; MECHANICAL VENTILATION; FLUID-MANAGEMENT;
D O I
10.1177/08971900221108713
中图分类号
R9 [药学];
学科分类号
1007 ;
摘要
Acute respiratory distress syndrome (ARDS) presents as an acute inflammatory lung injury characterized by refractory hypoxemia and non-cardiac pulmonary edema. An estimated 10% of patients in the intensive care unit and 25% of those who are mechanically ventilated are diagnosed with ARDS. Increased awareness is warranted as mortality rates remain high and delays in diagnosing ARDS are common. The COVID-19 pandemic highlights the importance of understanding ARDS management. Treatment of ARDS can be challenging due to the complexity of the disease state and conflicting existing evidence. Therefore, it is imperative that pharmacists understand both pharmacologic and non-pharmacologic treatment strategies to optimize patient care. This narrative review provides a critical evaluation of current literature describing management practices for ARDS. A review of treatment modalities and supportive care strategies will be presented.
引用
收藏
页码:1454 / 1471
页数:18
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