The chemical constituents from twigs of Hamamelis japonica and their antiviral activities

被引:1
|
作者
Park, SeonJu [1 ]
Nguyen Xuan Nhiem [2 ]
Song, Jae-Hyoung [3 ]
Oh, Mira [4 ]
Kim, Kil-Nam [1 ]
Ko, Hyun-Jeong [3 ]
Kim, Seung Hyun [4 ]
机构
[1] Korea Basic Sci Inst KBSI, Chuncheon Ctr, Chunchon, South Korea
[2] Vietnam Acad Sci & Technol, Inst Marine Biochem, Hanoi, Vietnam
[3] Kangwon Natl Univ, Coll Pharm, Lab Microbiol & Immunol, Chunchon, South Korea
[4] Yonsei Univ, Coll Pharm, Yonsei Inst Pharmaceut Sci, Incheon, South Korea
基金
新加坡国家研究基金会;
关键词
Hamamelis japonica; Hamamelidaceae; monoterpenoid glycosides; flavanol; antiviral activities; GLYCOSIDES; DERIVATIVES; GLUCOSIDE; TANNINS;
D O I
10.1080/14786419.2022.2094376
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
Three new monoterpenoid glycosides (1-3) and one new flavanol (4) along with 15 known compounds were isolated from the twig of Hamamelis japonica Sieb. et Zucc. The chemical constituent study of the twig of H. japonica has performed for the first time in the present investigation. Their structures were determined based on extensive spectroscopic methods including 1 D and 2 D NMR and CD spectra data. All isolated compounds were tested for their antiviral activities against HRV1B-, EV71-, PR8- and CVB3-infected Vero cells. Among the tested compounds, (-)-epigallocatechin 3-O-gallate exhibited the most consistent and effective antiviral activities against EV71 and PR8 infections.
引用
收藏
页码:863 / 870
页数:8
相关论文
共 50 条
  • [11] Chemical constituents of Anacolosa pervilleana and their antiviral activities
    Bourjot, Melanie
    Leyssen, Pieter
    Eydoux, Cecilia
    Guillemot, Jean-Claude
    Canard, Bruno
    Rasoanaivo, Philippe
    Gueritte, Francoise
    Litaudon, Marc
    FITOTERAPIA, 2012, 83 (06) : 1076 - 1080
  • [12] Antiviral and antiphlogistic activities of Hamamelis virginiana bark
    Erdelmeier, CAJ
    Cinatl, J
    Rabenau, H
    Doerr, HW
    Biber, A
    Koch, E
    PLANTA MEDICA, 1996, 62 (03) : 241 - 245
  • [13] Chemical Constituents from The Leaves and Twigs of Magnolia Decidua
    Zhou, Qi
    Wan, Jiang
    Jiang, Chun-Xiao
    Tong, Ying-Peng
    Xie, Zhen-Da
    Wang, Ting
    Xiao, Dao-An
    Xiao, Zhi-Yong
    Hu, Jin-Feng
    RECORDS OF NATURAL PRODUCTS, 2023, 17 (03) : 509 - 515
  • [14] Bioactive chemical constituents from the twigs of Salix glandulosa
    Suh, W. S.
    Kim, C. S.
    Park, K. J.
    Cha, J. M.
    Kim, D. H.
    Lee, K. R.
    PLANTA MEDICA, 2016, 82
  • [15] Chemical constituents from the twigs and leaves of Picrasma quassioides
    Zhou, Ya-Ling
    Bi, De-Wen
    Sun, Xiao-Rong
    Pang, Wen-Hui
    Li, Rui
    Qiu, Xiong
    Zhang, Rui-Han
    Zhang, Xing-Jie
    Li, Xiao-Li
    Xiao, Wei-Lie
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2023, 25 (10) : 968 - 975
  • [16] Chemical constituents from the twigs and leaves of Lyonia ovalifolia
    Zhao, De-Rui
    Su, Li-Hua
    Li, Rong-Tao
    Chen, Xuan-Qin
    Li, Hong-Mei
    BIOCHEMICAL SYSTEMATICS AND ECOLOGY, 2018, 78 : 1 - 4
  • [17] Chemical constituents from the twigs with leaves of Tetradium trichotomum
    Chen, Hong-Lian
    Yao, Jia-Ying
    Gao, Ming-Hui
    Tan, Jun-Jie
    Qu, Shi-Jin
    He, Shi-Jun
    Tan, Chang-Heng
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2024, 26 (11) : 1285 - 1291
  • [18] Phenolic constituents from twigs of Aleurites fordii and their biological activities
    Park, Kyoung Jin
    Suh, Won Se
    Yoon, Da Hye
    Kim, Chung Sub
    Kim, Sun Yeou
    Lee, Kang Ro
    BEILSTEIN JOURNAL OF ORGANIC CHEMISTRY, 2021, 17 : 2329 - 2339
  • [19] The Chemical constituents of the twigs of Ammopiptanthus nanus
    Ji, Teng-Fei
    Li, Jin
    Liang, Chun-Hui
    JOURNAL OF ASIAN NATURAL PRODUCTS RESEARCH, 2013, 15 (04) : 332 - 336
  • [20] Chemical Constituents of the Twigs of Caesalpinia mimosoides
    Dongyang He
    Ruijing Ma
    Yuanping Li
    Xunyun Yang
    Liqin Wang
    Chemistry of Natural Compounds, 2017, 53 : 545 - 547