Visible Light-Induced C-5 Selective C-H Radical Borylation of Imidazo[1,2-a]pyridines with NHC-Boranes

被引：23
|
作者：
Zheng, Huitao [1 ,2 ]
Lu, Hao [1 ,2 ]
Su, Chaobo [1 ,2 ]
Yang, Runlong [1 ,2 ]
Zhao, Limin [1 ,2 ]
Liu, Xiang [1 ,2 ]
Cao, Hua [1 ,2 ]
机构：
[1] Guangdong Pharmaceut Univ, Sch Chem & Chem Engn, Zhongshan 528458, Guangdong, Peoples R China
[2] Guangdong Pharmaceut Univ, Guangdong Cosmet Engn & Technol Res Ctr, 528458, Zhongshan, Guangdong, Peoples R China
来源：
CHINESE JOURNAL OF CHEMISTRY | 2023年 / 41卷 / 02期
关键词：
Photochemistry; Boron; C-H activation; Imidazo[1; 2-a]pyridines; Radicals; Synthetic methods; FUNCTIONALIZATION; DESIGN; ESTERS;
D O I：
10.1002/cjoc.202200568
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A visible-light-induced C-5 selective C-H borylation of imidazo[1,2-a]pyridines with NHC-BH3 via Minisci-type radical borylation reaction has been developed for the first time. The present sustainable protocol provides a new family of regioselectively C5-borylated imidazopyridines that would otherwise be difficult to prepare. It is a supplement to site-selective borylation of azines (nitrogen-containing aromatic heterocycles) and the assembly of sp(2) carbon-boron bond.
引用
收藏
页码：193 / 198
页数：6
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