Primary central nervous system lymphoma in a patient with multiple sclerosis using fingolimod

被引：3

作者：

Morillos, Matheus Bernardon ^{[1
]}

Pires de Aguiar, Paulo Henrique ^{[2
]}

Franceschini, Paulo Roberto ^{[3
]}

Duarte, Juliana Avila ^{[4
]}

Piccini, Cristian Daniel ^{[5
]}

Finkelsztejn, Alessandro ^{[1
]}

机构：

[1] Hosp Clin Porto Alegre, Dept Neurol, Porto Alegre, RS, Brazil

[2] Pontificia Univ Catolica Sao Paulo, Dept Neurol, Sao Paulo, Brazil

[3] Hosp Saude, Dept Neurosurg, Caxias Do Sul, RS, Brazil

[4] Hosp Clin Porto Alegre, Dept Internal Med, Porto Alegre, RS, Brazil

[5] Univ Fed Rio Grande do Sul, Fac Med, Rua Ramiro Barcelos 2400, BR-90035002 Porto Alegre, RS, Brazil

来源：

NEUROLOGICAL SCIENCES | 2023年 / 44卷 / 01期

关键词：

Lymphoma; Fingolimod; Multiple sclerosis; CNS; Primary; Brain; CELL LYMPHOMA;

D O I：

10.1007/s10072-022-06367-3

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Primary central nervous system lymphoma (PCNSL) is an uncommon lymphoproliferative disease associated with immunosuppression. Here, we report the case of a patient with multiple sclerosis, under treatment with fingolimod (FTY720, Gilenya) for 4 years, who developed this condition. Although the causal relationship cannot be established, there are cases in the literature that describe the appearance of lymphoma after the use of this medication. Considering the high mortality of PCNSL, epidemiological studies are necessary to establish a relationship between its arising and the use of immunosuppressants.

引用

页码：361 / 363

页数：3

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