Primary central nervous system lymphoma in a patient with multiple sclerosis using fingolimod

被引：3

作者：

Morillos, Matheus Bernardon ^{[1
]}

Pires de Aguiar, Paulo Henrique ^{[2
]}

Franceschini, Paulo Roberto ^{[3
]}

Duarte, Juliana Avila ^{[4
]}

Piccini, Cristian Daniel ^{[5
]}

Finkelsztejn, Alessandro ^{[1
]}

机构：

[1] Hosp Clin Porto Alegre, Dept Neurol, Porto Alegre, RS, Brazil

[2] Pontificia Univ Catolica Sao Paulo, Dept Neurol, Sao Paulo, Brazil

[3] Hosp Saude, Dept Neurosurg, Caxias Do Sul, RS, Brazil

[4] Hosp Clin Porto Alegre, Dept Internal Med, Porto Alegre, RS, Brazil

[5] Univ Fed Rio Grande do Sul, Fac Med, Rua Ramiro Barcelos 2400, BR-90035002 Porto Alegre, RS, Brazil

来源：

NEUROLOGICAL SCIENCES | 2023年 / 44卷 / 01期

关键词：

Lymphoma; Fingolimod; Multiple sclerosis; CNS; Primary; Brain; CELL LYMPHOMA;

D O I：

10.1007/s10072-022-06367-3

中图分类号：

R74 [神经病学与精神病学];

学科分类号：

摘要：

Primary central nervous system lymphoma (PCNSL) is an uncommon lymphoproliferative disease associated with immunosuppression. Here, we report the case of a patient with multiple sclerosis, under treatment with fingolimod (FTY720, Gilenya) for 4 years, who developed this condition. Although the causal relationship cannot be established, there are cases in the literature that describe the appearance of lymphoma after the use of this medication. Considering the high mortality of PCNSL, epidemiological studies are necessary to establish a relationship between its arising and the use of immunosuppressants.

引用

页码：361 / 363

页数：3

共 50 条

[1] Primary central nervous system lymphoma in a patient with multiple sclerosis using fingolimod
Matheus Bernardon Morillos
Paulo Henrique Pires de Aguiar
Paulo Roberto Franceschini
Juliana Ávila Duarte
Cristian Daniel Piccini
Alessandro Finkelsztejn
Neurological Sciences, 2023, 44 : 361 - 363
[2] A Case of Primary Central Nervous System Lymphoma That Developed in a Patient Receiving Fingolimod Therapy for Multiple Sclerosis
Takanashi, Kengo
Fukami, Shinjiro
Akimoto, Jiro
Matsubayashi, Jun
Kohno, Michihiro
CUREUS JOURNAL OF MEDICAL SCIENCE, 2023, 15 (12)
[3] PRIMARY CENTRAL-NERVOUS-SYSTEM LYMPHOMA IMITATES MULTIPLE-SCLEROSIS
DEANGELIS, LM
JOURNAL OF NEURO-ONCOLOGY, 1990, 9 (02) : 177 - 181
[4] The Direct Effects of Fingolimod in the Central Nervous System: Implications for Relapsing Multiple Sclerosis
Samuel F. Hunter
James D. Bowen
Anthony T. Reder
CNS Drugs, 2016, 30 : 135 - 147
[5] Hypothalamic dysfunction in a patient with primary lymphoma of the central nervous system
Darko Antic
Mihajlo Smiljanic
Jelena Bila
Snezana Jankovic
Milena Todorovic
Bosko Andjelic
Biljana Mihaljevic
Neurological Sciences, 2012, 33 : 387 - 390
[6] Hypothalamic dysfunction in a patient with primary lymphoma of the central nervous system
Antic, Darko
Smiljanic, Mihajlo
Bila, Jelena
Jankovic, Snezana
Todorovic, Milena
Andjelic, Bosko
Mihaljevic, Biljana
NEUROLOGICAL SCIENCES, 2012, 33 (02) : 387 - 390
[7] Primary mediastinal large B-cell lymphoma in a patient on Fingolimod for relapsing-remitting multiple sclerosis
Chacko, Joseph A.
Strati, Paolo
Stout, Paul W.
Archer, Robert L.
Baltz, Brad P.
Chacko, Joseph G.
MULTIPLE SCLEROSIS AND RELATED DISORDERS, 2021, 49
[8] Fingolimod-induced bladder lymphoma in a patient with multiple sclerosis
Vaheb, Saeed
Ghaffary, Elham Moases
Shaygannejad, Vahid
Mirmosayyeb, Omid
CLINICAL CASE REPORTS, 2023, 11 (04):
[9] The Development of Primary Central Nervous System B-Cell Lymphoma in Multiple Sclerosis
Lyons, Mark K.
Boucher, Orland K.
Birch, Barry D.
Patel, Naresh P.
NEUROHOSPITALIST, 2011, 1 (03) : 133 - 136
[10] Primary Central Nervous System Lymphoma in a Patient Treated With Natalizumab
Schweikert, Andreas
Kremer, Marcus
Ringel, Florian
Liebig, Thomas
Duyster, Justus
Stueve, Olaf
Hemmer, Bernhard
Berthele, Achim
ANNALS OF NEUROLOGY, 2009, 66 (03) : 403 - 406

← 1 2 3 4 5 →